ATG101 antibody

Principal name

ATG101 antibody

Alternative names for ATG101 antibody

C12orf44, PP894, Autophagy-related protein 101, UPF0453 protein C12orf44

SwissProt ID

Q2HJE0 (Bovin), Q6AY69 (Rat), Q6DE58 (Xenla), Q9BSB4 (Human), Q9D8Z6 (Mouse)

Gene ID

60673 (C12orf44), 68118 (9430023L20Rik), 300240 (RGD1359310)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of ATG101 antibody

Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG101 is a recently discovered protein that stabilizes ATG13, another autophagy protein that forms a complex with the mammalian homologs of ATG1, ULK1 and ULK2, and with FIP200. This complex is a target of TOR phosphorylation under normal conditions; inhibition of TOR by rapamycin or leucine deprivation leads to dephosphorylation of ATG13, ULK1 and ULK2, which then leads to autophagy. ATG101 also interacts with ULK1 and is essential for autophagy.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ATG101 (Center) antibody

  Rabbit Polyclonal ATG101 Antibody  
Western blot analysis of ATG101 in human liver tissue lysate with ATG101 antibody at (A) 1 and (B) 2 ug/mL. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ATG101 antibody

  Rabbit Polyclonal Anti-C12orf44 Antibody  
Host: Rabbit; Target Name: ATG101; Sample Tissue: COLO205 Whole Cell lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ATG101 antibody

  Rabbit Polyclonal Anti-C12orf44 Antibody  
Host: Rabbit; Target Name: C12orf44; Sample Tissue: Fetal Kidney lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

Atg101 - mouse gene knockout kit via CRISPR

Atg101 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Atg101 - mouse gene knockout kit via CRISPR

Atg101 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Atg101 - mouse gene knockout kit via CRISPR

Atg101 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Atg101 - mouse gene knockout kit via CRISPR

Atg101 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

C12orf44 - human gene knockout kit via CRISPR

C12orf44 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

C12orf44 - human gene knockout kit via CRISPR

C12orf44 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

C12orf44 - human gene knockout kit via CRISPR

C12orf44 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

C12orf44 - human gene knockout kit via CRISPR

C12orf44 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ATG101 (transcript variant 1)

  Recombinant protein of human chromosome 12 open reading frame 44 (C12orf44), transcript variant 1  
ATG101 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

ATG101 (full length, N-term HIS tag, transcript variant 2)

  Purified recombinant protein of Human chromosome 12 open reading frame 44 (C12orf44), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
ATG101 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ATG101 (Myc-DDK tagged) - Human chromosome 12 open reading frame 44 (C12orf44), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ATG101 (Myc-DDK tagged) - Human chromosome 12 open reading frame 44 (C12orf44), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, RGD1359310 (GFP-tagged ORF) - Rat similar to RIKEN cDNA 9430023L20 (RGD1359310), 200 uL, >10^7 TU/mL

Lenti ORF particles, RGD1359310 (GFP-tagged ORF) - Rat similar to RIKEN cDNA 9430023L20 (RGD1359310), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, RGD1359310 (Myc-DDK-tagged ORF) - Rat similar to RIKEN cDNA 9430023L20 (RGD1359310), 200 uL, >10^7 TU/mL

Lenti ORF particles, RGD1359310 (Myc-DDK-tagged ORF) - Rat similar to RIKEN cDNA 9430023L20 (RGD1359310), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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