ATG2B antibody

Principal name

ATG2B antibody

Alternative names for ATG2B antibody

Autophagy-related protein 2 homolog B, C14orf103

Gene ID

55102 (ATG2B)

Available reactivities

Hu (Human)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of ATG2B antibody

ATG2B Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. Another member of the autophagy family of proteins is ATG2B, one of two homologs of ATG2 that is essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. Relatively high rates of ATG2B mutations were observed in gastric and colorectal carcinomas, suggesting that deregulating the autophagy process may contribute to cancer development.

General readings

Velikkakath AK, Nishimura T, Oita E, et al. Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. Mol. Biol. Cell 2012; 23:896-909.

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ATG2B (N-term) antibody

Western blot analysis of ATG2B in K562 cell lysate with ATG2B antibody at (A) 1 and (B) 2 ug/ml Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ATG2B (N-term) Control Peptide

ATG2B
50 µg / €160.00
  Acris Antibodies GmbH

ATG2B antibody

Immunohistochemistry-Paraffin: ATG2B Antibody [NBP1-90731] Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells. Rabbit Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

ATG2B antibody

Immunohistochemistry-Paraffin: ATG2B Antibody [NBP1-90732] Immunohistochemical staining of human cerebral cortex shows cytoplasmic positivity in neuronal cells. Rabbit Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

ATG2B antibody

Immunohistochemistry-Paraffin: ATG2B Antibody [NBP1-90733] - Immunohistochemistry-Paraffin: ATG2B Antibody [NBP1-90733] Immunohistochemical staining of human heart muscle shows cytoplasmic positivity in myocytes. Rabbit Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

5 Item(s)

per page
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