ATIC / PURH antibody

Principal name

ATIC / PURH antibody

Alternative names for ATIC / PURH antibody

IMP cyclohydrolase, Inosinicase, IMP synthetase, Bifunctional purine biosynthesis protein PURH

SwissProt ID

O35567 (Rat), P31335 (Chick), P31939 (Human), Q0VCK0 (Bovin), Q9CWJ9 (Mouse)

Gene ID

471 (ATIC)

Available reactivities

Hu (Human), Dros (Drosophila), Frog, Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), African clawed frog, Xen (Xenopus), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ye (Yeast), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Flow Cytometry (F)

Background of ATIC / PURH antibody

The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-riboside, also designated ZMP, and its derivatives in erythrocytes and fibroblasts. Patients also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.

General readings

Geraghty,K.M., (2007) Biochem. J. 407 (2), 231-241

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ATIC / PURH antibody

Western blot analysis of extracts of various cell lines, using ATIC antibody. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ATIC / PURH antibody

Sample (30 ug of whole cell lysate). A: Hep G2 . 7.5% SDS PAGE. ATIC antibody. TA308474 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ATIC / PURH antibody

Western blot analysis of extract from Hela cells using anti-ATIC, clone F38P7H9. Mouse IgG1 F38P7H9 Purified Frog, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ATIC / PURH antibody

ATIC antibody - middle region validated by WB using Jurkat cell lysate at 5.0 ug/ml.ATIC is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ATIC / PURH antibody

Sample Type: 1. Hamster CHO K1 cells (20ug); 2. HeLa skin cells(20ug); 3. HEK273 cells (20ug); 4. Human Skin Fibroblats (100ug); Primary Dilution: 1: 800; Secondary Antibody: Clean-Blot IP detection Reagent and Kit; Secondary Dilution: 1: 2000; Image Subm Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ye, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ATIC / PURH antibody

Western blot detection of ATIC in various tissues and cell lysates using ATIC mouse mAb (1:1000 diluted).Predicted band size:64KDa.Observed band size:64KDa. Mouse IgG1 3H12-C9-H9 Purified WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ATIC / PURH antibody

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-ATIC monoclonal antibody. Mouse IgG1 OTI1D2 Purified Can, Hu, Mky, Ms, Rt F, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

ATIC / PURH antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (RC203490, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ATIC. Mouse IgG1 OTI2C10 Purified Can, Hu, Mky, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ATIC / PURH antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (RC203490, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ATIC. Mouse IgG1 OTI4A10 Purified Can, Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ATIC / PURH antibody

Figure 1. Spleen: Formalin-Fixed Paraffin-Embedded (FFPE) Mouse IgG1 F38 P7 H9 Purified Dros, Frog, Hu, Ms, Rt C, WB
0.2 mg / €340.00
  Acris Antibodies GmbH

ATIC / PURH antibody

ATIC / PURH Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

ATIC / PURH antibody

ATIC / PURH Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

ATIC / PURH antibody

Western Blot analysis of ATIC expression in transfected 293T cell line (H00000471-T02) by ATIC MaxPab polyclonal antibody.

Lane 1: ATIC transfected lysate(64.60 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

ATIC / PURH antibody

Western blot analysis of ATIC expression in HT-29 cell lysate in ATIC monoclonal antibody, clone F38 P7 H9 ( Cat # MAB1824 ). Mouse IgG1 F38 P7 H9 Frog, Hu, Ms, Rt C, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

ATIC / PURH antibody

Human kidney; ATIC antibody - middle region (ARP46094_T100) in Human kidney cells using Immunohistochemistry Rabbit Purified Bov, Can, Chk, Hu, Ms, Por, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

ATIC / PURH antibody

Human, Hamster; . Sample Type: 1. Hamster CHO K1 cells (20ug). 2. HeLa skin cells(20ug). 3. HEK273 cells (20ug). 4. Human Skin Fibroblats (100ug). Primary Dilution: 1:800. Secondary Antibody: Clean-Blot IP detection Reagent and Kit. Secondary Dilution: 1:2000. Image Submitted By: V. Skopova, M. Zikanova. Institute of Inherited Metabolic Disorders, Charles University in Prague and General Hopspital in Prague .; ATIC antibody - N-terminal region (ARP46095_T100) in Human, Hamster cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Dros, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

ATIC / PURH antibody

Immunofluorescence: ATIC Antibody [NBP1-32221]-  analysis of HeLa, using ATIC antibody at 1:200 dilution. Rabbit IgG Hu ICC/IF, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

ATIC / PURH antibody

Western Blot: ATIC Antibody [NBP1-56916] - This Anti-ATIC antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 5ug/ml. Rabbit Purified Can, Hu, Ms, Rt P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ATIC / PURH

ATIC / PURH Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

ATIC / PURH

ATIC / PURH Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

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