ATOH8 antibody

Principal name

ATOH8 antibody

Alternative names for ATOH8 antibody

hATH-6, hATH6, Protein atonal homolog 8, Helix-loop-helix protein hATH-6

SwissProt ID

Q96SQ7 (Human), Q99NA2 (Mouse)

Gene ID

84913 (ATOH8)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C)

Background of ATOH8 antibody

Basic helix-loop-helix (bHLH) transcription factors play important roles in differentiation processes during embryonic development of vertebrates. ATOH8 (MATH6) is a tissue-restricted member of the atonal superfamily of bHLH transcription factors that exhibits 43–57% identity in the bHLH domain with other mammalian atonal paralogs including the NeuroD and Neurogenin factors. In the mouse, ATOH8 has been implicated in the specification and differentiation of neuronal cell lineages in the brain and may also participate in kidney development. Recent studies show that ATOH8 is a novel component of the pancreatic transcriptional network during embryonic development and suggest a potential role as a modulator of the differentiation program initiated by the pro-endocrine factor Neurog3. It is indispensable for early embryonic development, suggesting a more widespread function for this factor in tissue-specific differentiation processes that are dependent on class II bHLH genes.

General readings

Wasserman,S.M., (2002) (er) Physiol. Genomics 12 (1), 13-23

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ATOH8 antibody

Western blot analysis of ATOH8 in A-20 cell lysate with ATOH8 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ATOH8 antibody

ATOH8 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ATOH8 antibody

WB Suggested Anti-ATOH8 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: COLO205 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ATOH8 Control Peptide

ATOH8
50 µg / €160.00
  Acris Antibodies GmbH

ATOH8 antibody

Human Jurkat; WB Suggested Anti-ATOH8 Antibody Titration: 2.5ug/ml. ELISA Titer: 1:12500. Positive Control: Jurkat cell lysate; ATOH8 antibody - N-terminal region (ARP39728_T100) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

ATOH8 (C-term) antibody

ATOH8 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

ATOH8 antibody

Immunohistochemistry-Paraffin: ATOH8 Antibody [NBP1-77347] - Mouse brain tissue with ATOH8 antibody at 5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ATOH8

ATOH8 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

ATOH8 overexpression lysate

ATOH8 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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