ATP1A3 antibody

Principal name

ATP1A3 antibody

Alternative names for ATP1A3 antibody

Sodium pump ATPase subunit alpha-3, Sodium/potassium-transporting ATPase subunit alpha-3, Na(+)/K(+) ATPase alpha-3 subunit, Na(+)/K(+) ATPase alpha(III) subunit

SwissProt ID

P06687 (Rat), P13637 (Human), Q6PIC6 (Mouse)

Gene ID

478 (ATP1A3)

Available reactivities

Can (Canine), GP (Guinea Pig), Hu (Human), Prim (Primate), Rb (Rabbit), Rt (Rat), Sh (Sheep), Bov (Bovine), Mky (Monkey), Ms (Mouse), Por (Porcine), Xen (Xenopus)

Available hosts

Mouse, Rabbit

Available applications

Flow Cytometry (F), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Neutralisation (NEUT), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of ATP1A3 antibody

The sodium/potassium ATPase is an integral membrane enzyme found in all cells of higher organisms and is responsible for the ATP-dependent transport of sodium and potassium across the cell membrane. This membrane-bound enzyme is related to a number of other ATPases including sarcoplasmic and endoplasmic reticulum calcium ATPase (SERCA) and plasma membrane calcium ATPase (PMCA). The sodium/potassium ATPase consists of a large, multipass, transmembrane catalytic subunit, termed the alpha subunit, and an associated smaller glycoprotein, termed the beta subunit. Studies indicate that there are three isoforms of the alpha subunit (alpha 1, alpha 2, alpha 3) and two isoforms of the beta subunit (beta 1 and beta 2) encoded by two multigene families.
The different isoforms of the sodium/potassium ATPase exhibit tissue-specific and developmental patterns of expression. The alpha 1 and beta mRNAs are present in all cell types examined, whereas the alpha 2 and alpha 3 mRNAs exhibit a more restricted pattern of cell-specific expression. The alpha-3 subunit has been found in neuronal and to skeletal and cardiac muscle, lung and stomach tissues.

General readings

Arystarkhova E & Sweadner KJ Isoform-specific monoclonal antibodies to Na,K-ATPase alpha subunits. Evidence for a tissue-specific post-translational modification of the alpha subunit. J Biol Chem 271:23407-17 (1996). PubMed PMID: 8798546
Lingrel JB et al. Molecular genetics of Na,K-ATPase. Prog Nucleic Acid Res Mol Biol 38:37-89 (1990). PubMed PMID: 2158121
Sweadner KJ Isozymes of the Na+/K+-ATPase. Biochim Biophys Acta 988:185-220 (1989). PubMed PMID: 2541792

5 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ATP1A3 antibody

ATP1A3 Mouse IgM 1D2 Ascites Hu E
0.2 ml / €370.00
  Abnova Taiwan Corp.

ATP1A3 antibody

ATP1A3 Mouse IgG1 XVIF9-G10 Ascites Bov, Can, GP, Hu, Mky, Ms, Rb, Rt, Sh C, ICC/IF, NEUT, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ATP1A3

ATP1A3 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

ATP1A3

ATP1A3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

ATP1A3

ATP1A3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

5 Item(s)

per page
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