ATP2A1 / SERCA1 antibody

Principal name

ATP2A1 / SERCA1 antibody

Alternative names for ATP2A1 / SERCA1 antibody

Calcium pump 1 ATPase, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform, SR Ca(2+)-ATPase 1, Endoplasmic reticulum class 1/2 Ca(2+) ATPase

SwissProt ID

O14983 (Human), P04191 (Rabit), P13585 (Chick), Q0VCY0 (Bovin), Q64578 (Rat), Q8R429 (Mouse)

Gene ID

487 (ATP2A1), 116601 (Atp2a1), 11937

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP)

Background of ATP2A1 / SERCA1 antibody

Three Ca2+ ATPases have been described in mammalian cells. They are located in the plasma membrane, endoplasmic reticulum or the Golgi apparatus. SERCA pumps are located in both the endoplasmic reticulum and in the Golgi membranes. They are known to transport two Ca2+ molecules per hydrolysis of one ATP. Their structure includes ten transmembrane domains and their main role is to remove cytoplasmic Ca2+ ions in order to promote muscle relaxation. In mammals three genes encode three SERCA pumps. Each transcript undergoes tissue-dependent altertive splicing. SERCA1a and 1b are expressed in adult and neotal skeletal muscle respectively. SERCA2a is also expressed in skeletal muscle, while SERCA2b is ubiquitously expressed. SERCA3 is expressed in a limited number of non-muscle cells. Although all SERCAs are regulated, SERCA2b undergoes extensive regulation at the protein level, such as protein-protein interaction, phosphorylation and glycosylation. The expression of SERCA1 in mice is essential whereas in human its absence is tolerated but is the cause of Brody myopathy. Malfunction of SERCAs is also observed in heart disease and different forms of cancer.

  1. Quick-Filters:
  2. Highly Validated (1)

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ATP2A1 / SERCA1 (522-613) antibody

Human Skeletal muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 1B11 Purified Hu E, ICC/IF, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

ATP2A1 / SERCA1 antibody

  Rabbit polyclonal anti-ATP2A1 antibody  
Western blot analysis of extracts from NIH/3T3 cells, A549 cells and HT-29 cells, using ATP2A1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ATP2A1 / SERCA1 antibody

  Rabbit Polyclonal Anti-SERCA1  
Western blot analysis of mouse C2C12 myoblast cell line lysate (lanes 1 and 3) and rat skeletal muscle membranes (lanes 2 and 4): 1, 2. Anti-SERCA1 antibody, (1:200). 3, 4. Anti-SERCA1 antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

ATP2A1 / SERCA1 antibody

Western blot analysis of extracts from HT-29/A549/NIH-3T3 cells, using ATP2A1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

ATP2A1 / SERCA1 antibody

Western blot analysis of extracts from HT-29/A549/NIH-3T3 cells, using ATP2A1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Atp2a1 - mouse gene knockout kit via CRISPR

Atp2a1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Atp2a1 - mouse gene knockout kit via CRISPR

Atp2a1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Atp2a1 - mouse gene knockout kit via CRISPR

Atp2a1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Atp2a1 - mouse gene knockout kit via CRISPR

Atp2a1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ATP2A1 / SERCA1 (transcript variant a)

  Recombinant protein of human ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (ATP2A1), transcript variant a  
ATP2A1 / SERCA1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ATP2A1 (mGFP-tagged) - Human ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (ATP2A1), transcript variant a, 200 uL, >10^7 TU/mL

Lenti ORF particles, ATP2A1 (mGFP-tagged) - Human ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (ATP2A1), transcript variant a, 200 uL, >10^7 TU/mL  
200 µl / €2,040.00
  OriGene Technologies, Inc.

Lenti ORF particles, ATP2A1 (Myc-DDK tagged) - Human ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (ATP2A1), transcript variant a , 200 uL, >10^7 TU/mL

Lenti ORF particles, ATP2A1 (Myc-DDK tagged) - Human ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (ATP2A1), transcript variant a , 200 uL, >10^7 TU/mL  
200 µl / €1,840.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Atp2a1 (GFP-tagged) - Mouse ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (Atp2a1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Atp2a1 (GFP-tagged) - Mouse ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (Atp2a1), 200 uL, >10^7 TU/mL  
200 µl / €1,770.00
  OriGene Technologies, Inc.

Lenti ORF particles, Atp2a1 (Myc-DDK-tagged) - Mouse ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (Atp2a1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Atp2a1 (Myc-DDK-tagged) - Mouse ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (Atp2a1), 200 uL, >10^7 TU/mL  
200 µl / €1,590.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Atp2a1 (GFP-tagged ORF) - Rat ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (Atp2a1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Atp2a1 (GFP-tagged ORF) - Rat ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (Atp2a1), 200 uL, >10^7 TU/mL  
200 µl / €1,770.00
  OriGene Technologies, Inc.

Lenti ORF particles, Atp2a1 (Myc-DDK-tagged ORF) - Rat ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (Atp2a1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Atp2a1 (Myc-DDK-tagged ORF) - Rat ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (Atp2a1), 200 uL, >10^7 TU/mL  
200 µl / €1,594.00
  OriGene Technologies, Inc.

16 Item(s)

per page
  • LinkedIn