ATP2B1 / PMCA1 antibody

Principal name

ATP2B1 / PMCA1 antibody

Alternative names for ATP2B1 / PMCA1 antibody

Plasma membrane calcium-transporting ATPase 1, Plasma membrane calcium ATPase isoform 1, Plasma membrane calcium pump isoform 1

SwissProt ID

G5E829, P11505 (Rat), P20020 (Human), P23220 (Pig), Q00804 (Rabit), Q98SH2 (Chick)

Gene ID

490 (ATP2B1)

Available reactivities

Hu (Human), Por (Porcine), Rt (Rat), Bov (Bovine), Can (Canine), Ms (Mouse)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P), Flow Cytometry (F)

Background of ATP2B1 / PMCA1 antibody

The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by altertive splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functiolly adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Altertively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq].

General readings

This product has been used in:Filoteo AG et al. Plasma membrane Ca2+ pump in rat brain. Patterns of alternative splices seen by isoform-specific antibodies. J Biol Chem 272:23741-7 (1997). PubMed PMID: 9295318
General / background references:Caride AJ et al. Detection of isoform 4 of the plasma membrane calcium pump in human tissues by using isoform-specific monoclonal antibodies. Biochem J 316 (Pt 1):353-9 (1996). PubMed PMID: 8645230

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ATP2B1 / PMCA1 (312-327) antibody

TA309535 (0.03µg/ml) staining of HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ATP2B1 / PMCA1 antibody

Detection limit for recombinant GST tagged ATP2B1 is approximately 0.3ng/ml as a capture antibody. Mouse IgG2a 3E2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ATP2B1 / PMCA1 antibody

ATP2B1 / PMCA1 Rabbit IgG Aff - Purified Hu, Por, Rt C, E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

ATP2B1 / PMCA1 antibody

ATP2B1 / PMCA1 Rabbit IgG Aff - Purified Hu, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

ATP2B1 / PMCA1 antibody

ATP2B1 / PMCA1 Rabbit Purified Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ATP2B1 / PMCA1

ATP2B1 / PMCA1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

ATP2B1 / PMCA1

ATP2B1 / PMCA1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

7 Item(s)

per page
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