ATP2B4 / PMCA4 antibody

Principal name

ATP2B4 / PMCA4 antibody

Alternative names for ATP2B4 / PMCA4 antibody

ATP2B2, MXRA1, Calcium pump 4 ATPase, Plasma membrane calcium-transporting ATPase 4, Plasma membrane calcium ATPase isoform 4, Plasma membrane calcium pump isoform 4, Matrix-remodeling-associated protein 1

SwissProt ID

P23634 (Human), Q64542 (Rat)

Gene ID

493 (ATP2B4), 29600 (Atp2b4)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Immunoprecipitation (IP), Frozen Sections (C), Paraffin Sections (P)

Background of ATP2B4 / PMCA4 antibody

ATP2B4 belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. ATP2B4 is the plasma membrane calcium ATPase isoform 4.The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified.

General readings

Dally,S., (2007) Platelets 18 (7), 543-549

10 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ATP2B4 / PMCA4 antibody

  Rabbit Polyclonal Anti-ATP2B4 Antibody  
WB Suggested Anti-ATP2B4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: 721_B cell lysate.There is BioGPS gene expression data showing that ATP2B4 is expressed in 721_B Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ATP2B4 / PMCA4 (N-term) antibody

ATP2B4 / PMCA4 Rabbit IgG Serum Hu, Ms, Rt C, IP, P, WB
0.2 ml / €420.00
  Swant

CRISPR

Catalog No. Species Donor Vector  

ATP2B4 - human gene knockout kit via CRISPR

ATP2B4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ATP2B4 - human gene knockout kit via CRISPR

ATP2B4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ATP2B4 / PMCA4 (transcript variant 2)

  Recombinant protein of human ATPase, Ca++ transporting, plasma membrane 4 (ATP2B4), transcript variant 2  
ATP2B4 / PMCA4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ATP2B4 (mGFP-tagged)-Human ATPase, Ca++ transporting, plasma membrane 4 (ATP2B4), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ATP2B4 (mGFP-tagged)-Human ATPase, Ca++ transporting, plasma membrane 4 (ATP2B4), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, ATP2B4 (mGFP-tagged) - Human ATPase, Ca++ transporting, plasma membrane 4 (ATP2B4), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, ATP2B4 (mGFP-tagged) - Human ATPase, Ca++ transporting, plasma membrane 4 (ATP2B4), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €2,370.00
  OriGene Technologies, Inc.

Lenti ORF particles, ATP2B4 (Myc-DDK-tagged)-Human ATPase, Ca++ transporting, plasma membrane 4 (ATP2B4), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ATP2B4 (Myc-DDK-tagged)-Human ATPase, Ca++ transporting, plasma membrane 4 (ATP2B4), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Atp2b4 (GFP-tagged ORF) - Rat ATPase, Ca++ transporting, plasma membrane 4 (Atp2b4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Atp2b4 (GFP-tagged ORF) - Rat ATPase, Ca++ transporting, plasma membrane 4 (Atp2b4), 200 uL, >10^7 TU/mL  
200 µl / €2,390.00
  OriGene Technologies, Inc.

Lenti ORF particles, Atp2b4 (Myc-DDK-tagged ORF) - Rat ATPase, Ca++ transporting, plasma membrane 4 (Atp2b4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Atp2b4 (Myc-DDK-tagged ORF) - Rat ATPase, Ca++ transporting, plasma membrane 4 (Atp2b4), 200 uL, >10^7 TU/mL  
200 µl / €2,155.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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