AUH antibody

Principal name

AUH antibody

Alternative names for AUH antibody

mitochondrial Methylglutaconyl-CoA hydratase, AU-specific RNA-binding enoyl-CoA hydratase, AU-binding protein/enoyl-CoA hydratase

SwissProt ID

Q13825 (Human), Q9JLZ3 (Mouse)

Gene ID

549 (AUH), 11992 (Auh)

Available reactivities

Hu (Human), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Bov (Bovine), Por (Porcine), Rb (Rabbit), Eq (Equine), GP (Guinea Pig), Ye (Yeast)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of AUH antibody

AU-specific RNA-binding enoyl-CoA hydratase (AUH) protein binds to the AU-rich element (ARE), a common element found in the 3\' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity. A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92% identity with the human protein. It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein. Human AUH is expressed as a single mRNA species of 1.8 kb, and translated as a 40-kDa precursor protein which is subsequently processed to a 32-kDa mature form.AU-specific RNA-binding enoyl-CoA hydratase (AUH) protein binds to the AU-rich element (ARE), a common element found in the 3\' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity. A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92% identity with the human protein. It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein. Human AUH is expressed as a single mRNA species of 1.8 kb, and translated as a 40-kDa precursor protein which is subsequently processed to a 32-kDa mature form.

General readings

Kurimoto K, et al. (2009). Proteins 75(2):360-72.
Mack M., et al. (2006). FEBS J. 273(9):2012-22.

17 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AUH antibody

WB Suggested Anti-Auh Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Mouse Heart Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

AUH antibody

WB Suggested Anti-AUH Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: HepG2 cell lysate; AUH is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ye P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

AUH antibody

AUH Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

AUH antibody

AUH Mouse IgG2a 2G12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

AUH (N-term) antibody

AUH Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

AUH antibody

Human Kidney; Rabbit Anti-AUH Antibody. Catalog Number: ARP40374. Paraffin Embedded Tissue: Human Kidney. Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; AUH antibody - C-terminal region (ARP40374_P050) in Human Kidney cells using Immunohistochemistry Rabbit Aff - Purified Can, Chk, Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

AUH antibody

AUH Rabbit Aff - Purified Can, Hu, Ms, Rt P, WB
50 µg / €440.00
  Novus Biologicals Inc.

AUH antibody

AUH Rabbit Aff - Purified Ms WB
50 µg / €440.00
  Novus Biologicals Inc.

AUH antibody

Immunohistochemistry-Paraffin: AUH Antibody [NBP1-86516] - Immunohistochemistry-Paraffin: AUH Antibody [NBP1-86516] Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

AUH

AUH Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

AUH (68-339, His-tag)

AUH Human Purified > 95 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

AUH (68-339, His-tag)

AUH Human Purified > 95 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

AUH

AUH Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

AUH

AUH Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

AUH

AUH Human Purified
0.1 mg / €380.00
  Novus Biologicals Inc.

AUH

AUH Human Purified
0.5 mg / €870.00
  Novus Biologicals Inc.

Lysates (Overexpressed)

Catalog No.    

AUH overexpression lysate

AUH overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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