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AVEN antibody

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Principal name

AVEN antibody

Alternative names for AVEN antibody

PDCD12, Cell death regulator Aven, Programmed cell death 12

SwissProt ID

Q9D9K3 (Mouse), Q9NQS1 (Human)

Gene ID

57099 (AVEN)

Ncbi ID

9606, NP_065104.1, NP_065104, NM_020371

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C)

Background of AVEN antibody

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Aven is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9. It is thought that Aven functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that Aven impedes Apaf-1-mediated caspase activation. Higher levels of Aven mRNA are seen in patients with acute leukemia than in control patients, suggesting that Aven may be useful as a prognostic indicator in leukemia patients. Despite its predicted molecular weight, Aven often migrates at 55 kDa in SDS-PAGE.

General readings

Figueroa B Jr, et al: (2004) Biotechnol Bioeng. 85(6), 589-600.
Cheng EH, et al: (2000) Mol Cell. 6(1), 31-40.

AP07274PU-N - AVEN
Skin: Formalin-Fixed Paraffin-Embedded (FFPE)
AP07274PU-N - AVEN
Pancreas: Formalin-Fixed Paraffin-Embedded (FFPE)
AP07657PU-N - AVEN
Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Testis.
H00057099-M08 - AVEN
AVEN monoclonal antibody (M08), clone 2B10. Western Blot analysis of AVEN expression in NIH/3T3(Cat # L018V1 ).
H00057099-M08 - AVEN
AVEN monoclonal antibody (M08), clone 2B10. Western Blot analysis of AVEN expression in Jurkat ( Cat # L017V1 ).
H00057099-M08 - AVEN
AVEN monoclonal antibody (M08), clone 2B10. Western Blot analysis of AVEN expression in PC-12(Cat # L012V1 ).
AM09049PU-N - AVEN
Paraffin embedded sections of human breast lobule tissue were incubated with anti-human PDCD12 (1:50) for 2 hours at room temperature. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB)
AM09049PU-N - AVEN
Paraffin embedded sections of human breast lobule tissue were incubated with anti-human PDCD12 (1:50) for 2 hours at room temperature. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB).
AM09049PU-N - AVEN
Western blot analysis: The extracts of mouse kidney (50 µg) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human PDCD12 (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
AM09049PU-N - AVEN
The extracts of mouse kidney (50ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human PDCD12 (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
MAB2053 - AVEN
The extract of mouse kidney ( 50 µg ) was resolved by SDS-PAGE and probed with AVEN monoclonal antibody, clone 3G4 ( Cat # MAB2053 ) ( 1:1000 ). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
PAB13091 - AVEN
Immunohistochemistry of AVEN in human spleen tissue with AVEN polyclonal antibody ( Cat # PAB13091 ) at 5 µg/ml.
PAB13091 - AVEN
Western blot analysis of AVEN in Raji cell lysate with AVEN polyclonal antibody ( Cat # PAB13091 ) at 1 µg/ml in ( A ) the presence and ( B ) the absence of blocking peptide.
PAB13093 - AVEN
Immunohistochemistry of AVEN in human spleen tissue with AVEN polyclonal antibody ( Cat # PAB13093 ) at 5 µg/ml.
PAB13093 - AVEN
Western blot analysis of AVEN in Raji cell lysate with AVEN polyclonal antibody ( Cat # PAB13093 ) at 1 µg/ml in ( A ) the presence and ( B ) the absence of blocking peptide.
AP30098PU-N - AVEN
Immunohistochemistry of Aven in human spleen tissue with AP30098PU-N Aven antibody at 5 μg/ml.
AP30098PU-N - AVEN
Western blot analysis of Aven in Raji cell lysate with AP30098PU-N Aven antibody at 1 μg/ml in (A) the presence and (B) the absence of blocking peptide.
AP30099PU-N - AVEN
Immunohistochemistry of Aven in human spleen tissue with AP30099PU-N Aven antibody at 5 μg/ml.
AP30099PU-N - AVEN
Western blot analysis of Aven in Raji cell lysate with AP30099PU-N Aven antibody at 1 μg/ml in (A) the presence and (B) the absence of blocking peptide.
C12070-1 - AVEN
Western blot analysis of extracts from COS7/LOVO cells, using AVEN Antibody. The lane on the right is treated with the synthesized peptide.
NBP1-76764 - AVEN
Immunohistochemistry-Paraffin: AVEN Antibody [NBP1-76764] - Human spleen tissue with Aven antibody at 5 u/mL. _x000d_
NBP1-76764 - AVEN
Western Blot: AVEN Antibody [NBP1-76764] - Analysis of Aven in Raji cell lysate with Aven antibody at 1 u/mL in (A) the presence and (B) the absence of blocking peptide._x000d_
NBP1-76771 - AVEN
Immunohistochemistry-Paraffin: AVEN Antibody [NBP1-76771] - Human spleen tissue with Aven antibody at 5 u/mL. _x000d_
NBP1-76771 - AVEN
Western Blot: AVEN Antibody [NBP1-76771] - Analysis of Aven in Raji cell lysate with Aven antibody at 1 u/mL in (A) the presence and (B) the absence of blocking peptide.
NBP1-95524 - AVEN
Immunohistochemistry-Paraffin: Aven Antibody (EPR4720) [NBP1-95524] - Aven.
NBP1-95524 - AVEN
Immunofluorescence: Aven Antibody (EPR4720) [NBP1-95524] HeLa cells using anti-Aven.
NBP1-95524 - AVEN
Western Blot: Aven Antibody (EPR4720) [NBP1-95524] - 7, and (D) Raji cell lysates using anti-Aven.
GTX50039 - AVEN
The extracts of mouse kidney (50ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human PDCD12 (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
GTX50039 - AVEN
Paraffin embedded sections of human breast lobule tissue were incubated with anti-human PDCD12 (1:50) for 2 hours at room temperature. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB)
TP303707 - AVEN
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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AVEN antibody
Paraffin embedded sections of human breast lobule tissue were incubated with anti-human PDCD12 (1:50) for 2 hours at room temperature. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB) Mouse IgG2a 3G4 Purified Hu, Ms E, P, WB
0.1 ml / €310.00
  Acris Antibodies GmbH
+3 additional images

Highly validated antibody!

AVEN antibody
Paraffin embedded sections of human breast lobule tissue were incubated with anti-human PDCD12 (1:50) for 2 hours at room temperature. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB) Mouse IgG2a 3G4 Purified Hu, Ms E, P, WB
50 µl / €230.00
  Acris Antibodies GmbH
+3 additional images

Highly validated antibody!

AVEN (C-term) antibody
Western blot analysis of Aven in Raji cell lysate with Aven antibody at 1 ug/ml in (A) the presence and (B) the absence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.
+2 additional images

AVEN (N-term) antibody
Western blot analysis of Aven in Raji cell lysate with Aven antibody at 1 ug/ml in (A) the presence and (B) the absence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.
+2 additional images

AVEN antibody
Western blot analysis of extracts from LOVO cells and COS-7 cells, using AVEN antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AVEN antibody
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using AVEN Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.
+1 additional image

AVEN antibody
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane 1-2: Raji cells, Hela cells, Primary antibody: AVEN Antibody at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.
+2 additional images

AVEN antibody
Skin: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH
+1 additional image

AVEN antibody
Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Testis. Rabbit Aff - Purified Hu, Ms, Rt P, WB
25 µg / €470.00
  Acris Antibodies GmbH

AVEN Control Peptide
AVEN
50 µg / €160.00
  Acris Antibodies GmbH

AVEN Control Peptide
AVEN
50 µg / €160.00
  Acris Antibodies GmbH

AVEN antibody
AVEN monoclonal antibody (M08), clone 2B10. Western Blot analysis of AVEN expression in NIH/3T3(Cat # L018V1 ). Mouse IgG2b 2B10 Purified Hu, Ms, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.
+2 additional images

AVEN antibody
The extract of mouse kidney ( 50 µg ) was resolved by SDS-PAGE and probed with AVEN monoclonal antibody, clone 3G4 ( Cat # MAB2053 ) ( 1:1000 ). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2a 3G4 Hu, Ms E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

AVEN antibody
Immunohistochemistry of AVEN in human spleen tissue with AVEN polyclonal antibody ( Cat # PAB13091 ) at 5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.
+1 additional image

AVEN antibody
Immunohistochemistry of AVEN in human spleen tissue with AVEN polyclonal antibody ( Cat # PAB13093 ) at 5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.
+1 additional image

AVEN antibody
Western blot analysis of extracts from COS7/LOVO cells, using AVEN Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

AVEN antibody
Western blot analysis of extracts from COS7/LOVO cells, using AVEN Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

AVEN antibody
AVEN Mouse IgG2a 3G4 Purified Hu E, P, WB
0.1 ml / €380.00
  Novus Biologicals Inc.

AVEN antibody
Immunohistochemistry-Paraffin: AVEN Antibody [NBP1-76764] - Human spleen tissue with Aven antibody at 5 u/mL. _x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.
+1 additional image

AVEN antibody
Immunohistochemistry-Paraffin: AVEN Antibody [NBP1-76771] - Human spleen tissue with Aven antibody at 5 u/mL. _x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.
+1 additional image

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