BACH1 antibody

Principal name

BACH1 antibody

Alternative names for BACH1 antibody

HA2303, Transcription regulator protein BACH1, BTB and CNC homolog 1, basic leucine zipper transcription factor 1

SwissProt ID

O14867 (Human), P97302 (Mouse)

Gene ID

571 (BACH1), 12013 (Bach1)

Available reactivities

Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat), Chimp (Chimpanzee)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Flow Cytometry (F)

Background of BACH1 antibody

Members of the small Maf family (MafK, MafF, and MafG) are basic region leucine zipper (bZip) proteins that can function as transcriptional activators or repressors. They dimerize with other proteins and bind DNA to either represse or activate transcription depending on the dimer compositions. BACH1 and BACH2, heterodimerization partners of MafK, are members of a novel family of BTB/POZ-basic region leucine zipper (bzip) factors. BACH1 and BACH2 have significant similarity to each other in BTB domain and Cap‘n’ collar-type bZip domain but are otherwise divergent. BACH1 appears ubiquitous, whereas BACH2 is restricted to monocytes, neuronal cells and is abundantly expressed in the early stages of B-cell differentiation. BACH2, a 841 amino acid polypeptide, is an Nrf2-related transcription repressor and a tissue-specific partner of the Maf oncoprotein family. In culture cells, BACH2 is localized to the cytoplasm through its C-terminal cytoplasmic localization signal (CLS). Oxidative stressors aborted the CLS activity and induce nuclear accumulation of BACH2, which mediates nucleocytoplasmic communciation to couple oxidative stress and transcription repression in mammalian cells. BACH2 heterodimerizes with MAZR through its BTB/POZ domain to activate transcription. BACH2 also plays an important role in the regulation of B cell development.

General readings

Litman,R., et al., (2005) Cancer Cell 8 (3), 255-265

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BACH1 antibody

  BACH1 mouse monoclonal antibody, clone OTI4E11 (formerly 4E11)  
Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-BACH1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504484) Mouse IgG1 OTI4E11 Purified Hu F, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

BACH1 antibody

  Rabbit polyclonal anti-BACH1 antibody  
Western blot analysis of extracts from HeLa cells, HepG2 cells and 293 cells, using BACH1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BACH1 antibody

  Rabbit Polyclonal Anti-BACH1 Antibody  
WB Suggested Anti-BACH1 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BACH1 antibody

Western blot (WB) analysis of BACH1 antibody (Cat.-No.: AP06634PU-N) in extracts from HeLa cells. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

BACH1 (Isoform 1) (92-104) antibody

Skeletal muscle: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

BACH1 (C-term) antibody

BACH1 Antibody (C-term) (Cat. #AP50333PU-N) western blot analysis in ZR-75-1 cell line lysates (35µg/lane).This demonstrates the BACH1 antibody detected the BACH1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BACH1 antibody

Immunofluorescence analysis of HeLa cells, using BACH1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

BACH1 antibody

Immunofluorescence analysis of HeLa cells, using BACH1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

BACH1 - human gene knockout kit via CRISPR

BACH1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

BACH1 - human gene knockout kit via CRISPR

BACH1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

BACH1 - human gene knockout kit via CRISPR

BACH1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

BACH1 - human gene knockout kit via CRISPR

BACH1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bach1 - mouse gene knockout kit via CRISPR

Bach1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Bach1 - mouse gene knockout kit via CRISPR

Bach1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bach1 - mouse gene knockout kit via CRISPR

Bach1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bach1 - mouse gene knockout kit via CRISPR

Bach1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

BACH1 (transcript variant 2)

  Recombinant protein of human BTB and CNC homology 1, basic leucine zipper transcription factor 1 (BACH1), transcript variant 2  
BACH1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

BACH1 (transcript variant 1)

  Recombinant protein of human BTB and CNC homology 1, basic leucine zipper transcription factor 1 (BACH1), transcript variant 1  
BACH1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

BACH1 overexpression lysate

BACH1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BACH1 (mGFP-tagged) - Human BTB and CNC homology 1, basic leucine zipper transcription factor 1 (BACH1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, BACH1 (mGFP-tagged) - Human BTB and CNC homology 1, basic leucine zipper transcription factor 1 (BACH1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

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