Bacillus anthracis lethal factor antibody

Principal name

Bacillus anthracis lethal factor antibody

Alternative names for Bacillus anthracis lethal factor antibody

lef, pXO1-107, BXA0172, Anthrax lethal toxin endopeptidase component

SwissProt ID

P15917 (Bacan)

Gene ID

1158731 (lef), 84168 (ANTXR1), 3361711 (P15917)

Available reactivities

Hu (Human), Bac (Bacteria)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), ELISA (detection) (E(detection)), ELISA (capture) (E(capture)), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Bacillus anthracis lethal factor antibody

The protease enzyme Lethal Factor (LF) is one of the three proteins (LF, EF & PA) composing the anthrax toxin produced by Bacillus anthracis, a bacteria which can infect many mammalian species and that may be fatal. LF is not toxic by itself, but when associated with Protective Antigen (PA), can then gain entry to cells. Once inside the cell, LF then cleaves the N terminal of most dual specificity mitogen activated protein kinase kinases (MAPKKs or MAP2Ks) (except for MAP2K5). Cleavage invariably occurs within the N terminal proline rich region preceding the kinase domain, thus disrupting a sequence involved in directing specific protein protein interactions necessary for the assembly of signaling complexes. There may be other cytosolic targets of LF involved in cytotoxicity. The proteasome may mediate a toxic process initiated by LF in the cell cytosol involving degradation of unidentified molecules that are essential for macrophage homeostasis. This is an early step in LF intoxication, but it is downstream of the cleavage by LF of MEK1 or other putative substrates.

19 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Bacillus anthracis lethal factor Control Peptide

Bacillus anthracis lethal factor
50 µg / €160.00
  Acris Antibodies GmbH

Bacillus anthracis lethal factor (Center) antibody

Bacillus anthracis lethal factor Rabbit IgG Aff - Purified Bac E
0.1 mg / €360.00
  Acris Antibodies GmbH

Bacillus anthracis lethal factor Control Peptide

Bacillus anthracis lethal factor
50 µg / €160.00
  Acris Antibodies GmbH

Bacillus anthracis lethal factor (C-term) antibody

Bacillus anthracis lethal factor Rabbit IgG Aff - Purified Bac E
0.1 mg / €360.00
  Acris Antibodies GmbH

Bacillus anthracis lethal factor antibody

Bacillus anthracis lethal factor Mouse IgG1 BAL0105 Bac E
0.2 mg / €470.00
  Abnova Taiwan Corp.

Bacillus anthracis lethal factor antibody

Bacillus anthracis lethal factor Mouse IgG1 BAL0106 Bac E
0.2 mg / €470.00
  Abnova Taiwan Corp.

Bacillus anthracis lethal factor antibody

Bacillus anthracis lethal factor Mouse IgG1 LFA58 Bac E
0.2 mg / €470.00
  Abnova Taiwan Corp.

Bacillus anthracis lethal factor antibody

Bacillus anthracis lethal factor Mouse IgG2a LFA27 Bac E
0.2 mg / €470.00
  Abnova Taiwan Corp.

Bacillus anthracis lethal factor antibody

Bacillus anthracis lethal factor Rabbit IgG Bac E
0.1 mg / €390.00
  Abnova Taiwan Corp.

Bacillus anthracis lethal factor antibody

Bacillus anthracis lethal factor Rabbit IgG Bac E
0.1 mg / €390.00
  Abnova Taiwan Corp.

Bacillus anthracis lethal factor antibody

Bacillus anthracis lethal factor Mouse IgG1 BAL105 Purified E, E(detection)
1 mg / €390.00
  HyTest Ltd.

Bacillus anthracis lethal factor antibody

Bacillus anthracis lethal factor Mouse IgG1 BAL106 Purified E, E(capture)
1 mg / €390.00
  HyTest Ltd.

Bacillus anthracis lethal factor antibody

Bacillus anthracis lethal factor Mouse IgG2a LFA27 Purified E, E(detection)
1 mg / €390.00
  HyTest Ltd.

Bacillus anthracis lethal factor antibody

Bacillus anthracis lethal factor Mouse IgG1 LFA58 Purified E, E(capture)
1 mg / €390.00
  HyTest Ltd.

Bacillus anthracis lethal factor antibody

Western Blot: Anthrax LF Antibody (5F502.2) [NB100-56592] - Western blot analysis of Anthrax LF in recombinant protein using NB100-56592 at 0.1 ug/ml. Mouse IgG1 5F502.2 Aff - Purified Hu WB
0.1 mg / €340.00
  Novus Biologicals Inc.

Bacillus anthracis lethal factor antibody

Western Blot: Anthrax LF Antibody [NB100-56668] - Western blot analysis of Anthrax LF in recombinant protein using NB100-56668 (lane B) at 1:1000 dilution. Lane A shows the pre-bleed. Rabbit IgG Serum Hu WB
0.2 ml / €320.00
  Novus Biologicals Inc.

Bacillus anthracis lethal factor antibody

Bacillus anthracis lethal factor Mouse IgG1 LFA58 Purified Bac E
0.2 mg / €290.00
  Novus Biologicals Inc.

Bacillus anthracis lethal factor antibody

Bacillus anthracis lethal factor Mouse IgG2a LFA27 Purified Bac E
0.2 mg / €290.00
  Novus Biologicals Inc.

Bacillus anthracis lethal factor antibody

Bacillus anthracis lethal factor Mouse IgG1 BAL0105 Bac E
0.2 mg / €290.00
  Novus Biologicals Inc.

19 Item(s)

per page
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