BAG2 antibody

Principal name

BAG2 antibody

Alternative names for BAG2 antibody

BAG-2, BAG family molecular chaperone regulator 2, Bcl-2-associated athanogene 2

SwissProt ID

O95816 (Human), Q3ZBG5 (Bovin), Q91YN9 (Mouse)

Gene ID

9532 (BAG2), 213539 (Bag2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of BAG2 antibody

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

General readings

Dai Q, Qian SB, Li HH, McDonough H, Borchers C, Huang D, Takayama S, Younger JM, Ren HY, Cyr DM, Patterson C.
Regulation of the cytoplasmic quality control protein degradation pathway by BAG2.
J Biol Chem. 2005 Nov 18;280(46):38673-81. Epub 2005 Sep 16.
PMID: 16169850

15 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BAG2 (C-term) antibody

  Goat Polyclonal Antibody against BAG2  
TA302728 (0.3µg/ml) staining of Hela lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

BAG2 - human gene knockout kit via CRISPR

BAG2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

BAG2 - human gene knockout kit via CRISPR

BAG2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

BAG2 - human gene knockout kit via CRISPR

BAG2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

BAG2 - human gene knockout kit via CRISPR

BAG2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bag2 - mouse gene knockout kit via CRISPR

Bag2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Bag2 - mouse gene knockout kit via CRISPR

Bag2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bag2 - mouse gene knockout kit via CRISPR

Bag2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bag2 - mouse gene knockout kit via CRISPR

Bag2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

BAG2 (1-211, His-tag)

BAG2 Human Purified > 95 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

BAG2 (1-211, His-tag)

BAG2 Human Purified > 95 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BAG2 (mGFP-tagged) - Human BCL2-associated athanogene 2 (BAG2), 200 uL, >10^7 TU/mL

Lenti ORF particles, BAG2 (mGFP-tagged) - Human BCL2-associated athanogene 2 (BAG2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, BAG2 (Myc-DDK tagged) - Human BCL2-associated athanogene 2 (BAG2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, BAG2 (Myc-DDK tagged) - Human BCL2-associated athanogene 2 (BAG2) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Bag2 (GFP-tagged) - Mouse BCL2-associated athanogene 2 (Bag2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Bag2 (GFP-tagged) - Mouse BCL2-associated athanogene 2 (Bag2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bag2 (Myc-DDK-tagged) - Mouse BCL2-associated athanogene 2 (Bag2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Bag2 (Myc-DDK-tagged) - Mouse BCL2-associated athanogene 2 (Bag2), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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