BAIAP2 antibody

Principal name

BAIAP2 antibody

Alternative names for BAIAP2 antibody

BAI1-associated protein 2, BAI-associated protein 2, BAP2, FLAF3, IRSp53/58, IRS-58, IRSp53, Brain-specific angiogenesis inhibitor 1-associated protein 2, Insulin receptor substrate p53, Insulin receptor substrate protein of 53 kDa, Insulin receptor substrate p53/p58, Fas ligand-associated factor 3

SwissProt ID

Q5EAD0 (Bovin), Q6GMN2 (Rat), Q8BKX1 (Mouse), Q9UQB8 (Human)

Gene ID

10458 (BAIAP2), 108100 (Baiap2), 117542

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), EPair for Elisa (EPair), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of BAIAP2 antibody

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kise substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neurol growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal domint neurodegenerative disease. Altertive splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009].

General readings

Oda K, Shiratsuchi T, Nishimori H, Inazawa J, Yoshikawa H, Taketani Y, Nakamura Y, Tokino T.
Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1.
Cytogenet Cell Genet. 1999;84(1-2):75-82.
PMID: 10343108

  • LinkedIn