BAP1 antibody

Principal name

BAP1 antibody

Alternative names for BAP1 antibody

BAP-1, KIAA0272, hucep-6, BRCA1-associated protein 1, Cerebral protein 6, Ubiquitin carboxyl-terminal hydrolase BAP1

SwissProt ID

Q92560 (Human), Q99PU7 (Mouse)

Gene ID

8314 (BAP1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), PLA/Proximity ligation assay (PLA)

Background of BAP1 antibody

This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as BASC for BRCA1-associated genome surveillance complex. This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complex. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants have been described for this gene but only some have had their full-length natures identified. Transcript Variant: This variant (BRCA1a') uses different splice site in the 5' UTR when compared to variant BRCA1a. It encodes the full-length BRCA1 protein (isoform 1) which is also known as p220. Variants BRCA1a and BRCA1b also encode the full-length BRCA1 protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Jensen, D. E.; Proctor, M.; Marquis, S. T.; Gardner, H. P.; Ha, S. I.; Chodosh, L. A.; Ishov, A. M.; Tommerup, N.; Vissing, H.; Sekido, Y.; Minna, J.; Borodovsky, A.; Schultz, D. C.; Wilkinson, K. D.; Maul, G. G.; Barlev, N.; Berger, S. L.; Prendergast, G. C.; Rauscher, F. J., III : BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression. Oncogene 16: 1097-1112, 1998.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BAP1 antibody

Detection of BAP1 in HeLa WCE  (2ug/ml) Mouse IgG1 1G8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BAP1 antibody

ELISA: BAP1 Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

BAP1 antibody

Lane 1: Rat Testicular tissue Lysate
Lane 2: Rat Ovarian tissue Lysate Mouse IgG1 BP-1 Purified Hu ICC/IF, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

BAP1 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BAP1 (C-term) antibody

Western Blot analysis using anti-BAP1 Pab (C-term) (Cat.#AP12078PU-N) to detect BAP1 in SK-BR-3 cell lysate. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BAP1 antibody

Immunofluorescence of purified MaxPab antibody to BAP1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

BAP1 antibody

Immunofluorescence of purified MaxPab antibody to BAP1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

BAP1 antibody

BAP1 Mouse IgG1 BP-1 Hu ICC/IF, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

BAP1 antibody

Western blot analysis of BAP1 in HeLa whole celll lysate using BAP1 monoclonal antibody, clone 1G8 ( Cat # MAB2377 ). Mouse IgG1 1G8 Hu WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

BAP1 antibody

The BAP1 polyclonal antibody ( Cat # PAB1685 ) is used in Western blot to detect BAP1 in SK-BR-3 cell lysate. Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

BAP1 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with BAP1 polyclonal antibody ( Cat # PAB1686 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu, Ms E, P
0.4 ml / €390.00
  Abnova Taiwan Corp.

BAP1 antibody

BAP1 Mouse IgG1 BP-1 Ascites Hu ICC/IF, WB
0.1 mg / €290.00
  Boster Immunoleader

BAP1 antibody

ELISA: BAP1 Antibody [35670002] Rabbit Hu E, WB
50 µg / €400.00
  Novus Biologicals Inc.

BAP1 antibody

BAP1 Mouse IgG1 1G8 Biotin Hu WB
0.1 ml / €360.00
  Novus Biologicals Inc.

BAP1 antibody

BAP1 Mouse IgG1 1G8 DyLight488 Hu WB
0.1 ml / €390.00
  Novus Biologicals Inc.

BAP1 antibody

BAP1 Mouse IgG1 1G8 HRP Hu WB
0.1 ml / €390.00
  Novus Biologicals Inc.

BAP1 antibody

BAP1 Mouse IgG1 1G8 Purified Hu ICC/IF, WB
25 µl / €170.00
  Novus Biologicals Inc.

BAP1 antibody

Western Blot : BAP1 Antibody [NBP1-26627]-Whole cell lysate from HeLa cells. Antibodies: Affinity purified rabbit  used for IP at 10 mcg/mg lysate. Rabbit IgG Aff - Purified Hu IP
0.1 mg / €440.00
  Novus Biologicals Inc.

BAP1 antibody

Western Blot: BAP1 Antibody [NBP1-26628]-Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded)  from HeLa cells.  Affinity purified rabbit anti-BAP1 used for WB at 0.4 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 10 mcg/mg lysate.  BAP1 was also immunoprecipitated by rabbit anti-BAP1 antibody NBP1-26627, which recognizes an upstream epitope. Rabbit IgG Aff - Purified Hu IP, PLA, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

BAP1 antibody

Immunohistochemistry-Paraffin: BAP1 Antibody [NBP1-83149] - Immunohistochemical staining of human pancreas shows distinct nucleolar positivity in exocrine cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

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