Basophils antibody

Principal name

Basophils antibody

Alternative names for Basophils antibody

Basophil cells

Available reactivities

Hu (Human)

Available hosts

Mouse

Available applications

Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Western blot / Immunoblot (WB)

Background of Basophils antibody

Basophils and mast cells are multifunctional hematopoietic effector cells involved in allergic and inflammatory reactions. Immediate allergy is caused by release of chemical mediators by these cell types. In human peripheral blood, 212H6.16 is an antibody specific to a yet non-identified cell-surface structure (~30KDa in reduced WB conditions and ~46KDa in non-reduced WB conditions) present on basophils. 212H6.16 does not induce basophil degranulation, and is therefore a valuable tool for the isolation and study of human basophils. Tonsillar epithelium and skin keratinocytes are also stained by 212H6 in situ: antigen expression in tonsil is restricted to cells lining the epithelial crypts.
(Bendriss-Vermare N.et al, Leukocyte Typing VII, White Cell Differentiation Antigen MC13, part 9, myeloid cells, 425-30, 2001; Editor Mason)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Basophils antibody

IHC staining of human tonsil epithelial crypts with clone 212H6 (DDX0030). Mouse IgM 212H6.16 Purified Hu C, F, WB
50 µg / €330.00
  Dendritics SAS

Basophils antibody

IHC staining of human skin frozen section with clone 212H6 (DDX0030) (normal skin) Mouse IgM 212H6.16 Alexa Fluor 488 Hu F
50 µg / €390.00
  Dendritics SAS

Basophils antibody

IHC staining of human skin frozen section with clone 212H6 (DDX0030) (normal skin) Mouse IgM 212H6.16 Alexa 546 Hu ICC/IF
50 µg / €390.00
  Dendritics SAS

Basophils antibody

IHC staining of human skin frozen section with clone 212H6 (DDX0030) (psoriasis) Mouse IgM 212H6.16 Biotin Hu F, ICC/IF
50 µg / €360.00
  Dendritics SAS

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