BCAS3 / GAOB1 antibody

Principal name

BCAS3 / GAOB1 antibody

Alternative names for BCAS3 / GAOB1 antibody

Maab1 protein, Breast carcinoma-amplified sequence 3

SwissProt ID

Q8CCN5 (Mouse), Q9H6U6 (Human)

Gene ID

54828 (BCAS3), 192197 (Bcas3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of BCAS3 / GAOB1 antibody

BCAS3 (breast carcinoma amplified sequence 3), also designated MAAB or GAOB1, is a 913 amino acid protein that is believed to be involved in breast cancer progression. The gene is regulated by ERå (estrogen receptor alpha) and expressed in multiple tissues, including malignant human brain lesions. It is overexpressed and amplified in breast cancer cell lines. BCAS3 contains three WD40 repeat regions, a bromodomain, a rare zinc-finger motif, four probable DNA-binding domains, and two kinase-inducible phosphorylation domains. Five variants are produced due to alternative splicing. BCAS3 interacts with histone H3 and PCAF, which is indicative of histone acetyltransferase activity. BCAS3 also exhibits ERå transactiviation activity by acting as a coactivator with PELP1 or MTA1. The amplification and translocation between the BCAS3 gene and the BCAS4 gene results in a fusion transcript is overexpressed in MCF-7 cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BCAS3 / GAOB1 antibody

  Rabbit Polyclonal BCAS3 Antibody  
Western blot analysis of BCAS3 in rat brain tissue lysate with BCAS3 antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BCAS3 / GAOB1 antibody

  Rabbit polyclonal anti-BCAS3 antibody  
Western blot analysis of extracts from 293 cells, using BCAS3 Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BCAS3 / GAOB1 antibody

  Rabbit Polyclonal Anti-BCAS3 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using (BCAS3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

BCAS3 / GAOB1 (C-term) antibody

Western blot analysis of BCAS3 (arrow) using rabbit polyclonal BCAS3 Antibody (C-term) (AP11409PU-N). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the BCAS3 gene (Lane 2) (Origene Technologies). Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BCAS3 / GAOB1 (N-term) antibody

Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

BCAS3 - human gene knockout kit via CRISPR

BCAS3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

BCAS3 - human gene knockout kit via CRISPR

BCAS3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

BCAS3 - human gene knockout kit via CRISPR

BCAS3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

BCAS3 - human gene knockout kit via CRISPR

BCAS3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bcas3 - mouse gene knockout kit via CRISPR

Bcas3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Bcas3 - mouse gene knockout kit via CRISPR

Bcas3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bcas3 - mouse gene knockout kit via CRISPR

Bcas3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bcas3 - mouse gene knockout kit via CRISPR

Bcas3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

BCAS3 / GAOB1 (transcript variant 2)

  Recombinant protein of human breast carcinoma amplified sequence 3 (BCAS3), transcript variant 2  
BCAS3 / GAOB1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BCAS3 (mGFP-tagged)-Human breast carcinoma amplified sequence 3 (BCAS3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, BCAS3 (mGFP-tagged)-Human breast carcinoma amplified sequence 3 (BCAS3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, BCAS3 (mGFP-tagged) - Human breast carcinoma amplified sequence 3 (BCAS3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, BCAS3 (mGFP-tagged) - Human breast carcinoma amplified sequence 3 (BCAS3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, BCAS3 (Myc-DDK-tagged)-Human breast carcinoma amplified sequence 3 (BCAS3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, BCAS3 (Myc-DDK-tagged)-Human breast carcinoma amplified sequence 3 (BCAS3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, BCAS3 (Myc-DDK tagged) - Human breast carcinoma amplified sequence 3 (BCAS3), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, BCAS3 (Myc-DDK tagged) - Human breast carcinoma amplified sequence 3 (BCAS3), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Bcas3 (GFP-tagged) - Mouse breast carcinoma amplified sequence 3 (Bcas3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Bcas3 (GFP-tagged) - Mouse breast carcinoma amplified sequence 3 (Bcas3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,680.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bcas3 (GFP-tagged) - Mouse breast carcinoma amplified sequence 3 (Bcas3), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, Bcas3 (GFP-tagged) - Mouse breast carcinoma amplified sequence 3 (Bcas3), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,670.00
  OriGene Technologies, Inc.

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