BCKDHA antibody

Principal name

BCKDHA antibody

Alternative names for BCKDHA antibody

alpha-keto acid dehydrogenase, BCKDE1A, 2-oxoisovalerate dehydrogenase subunit alpha mitochondrial, Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain

SwissProt ID

P11178 (Bovin), P11960 (Rat), P12694 (Human), P50136 (Mouse)

Gene ID

593 (BCKDHA), 2859355 (Q6GE90)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish), Eq (Equine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of BCKDHA antibody

The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO2. It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).The BCKDHA gene encodes the E1-alpha subunit of the branched-chain alpha-keto acid (BCAA) dehydrogenase complex (BCKD; EC 1.2.4.4), an inner-mitochondrial enzyme complex that catalyzes the oxidative decarboxylation of the branched-chain alpha-ketoacids derived from isoleucine, leucine, and valine. This reaction is the second major step in the catabolism of the branched-chain amino acids (Wynn et al., 1998 [PubMed 9582350]). The BCKD complex consists of 3 catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a homo-24-meric dihydrolipoyl transacylase (E2; MIM 248610), and a homodimeric dihydrolipoamide dehydrogenase (E3; MIM 238331). E1 is a thiamine pyrophosphate (TPP)-dependent enzyme. The reaction is irreversible and constitutes the first committed step in BCAA oxidation. The BCKDHB gene (MIM 248611) encodes the beta subunit of E1. The complex also contains 2 regulatory enzymes, a kinase and a phosphorylase.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-675 BI910860.1 12-686 676-1196 BG742673.1 80-600 1197-1731 BM702667.1 48-582 1732-1763 BE223026.1 1-32 c 1764-1781 BQ018849.1 1-18 c

General readings

Funchal, C., et al. (2005) Metab. Brain Dis. 20: 205-217.

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BCKDHA antibody

1Hum. Adult Placenta; Host: Rabbit; Target Name: SERPINA3; Sample Tissue: Human Adult Placenta; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Eq, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

BCKDHA (C-term) antibody

Western blot analysis of BCKDHA Antibody (C-term) (AP17149PU-N) in Jurkat cell line lysates (35 µg/lane). BCKDHA (arrow) was detected using the purified Pab. Rabbit Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BCKDHA antibody

BCKDHA polyclonal antibody (A01), Lot # 051212JC01 Western Blot analysis of BCKDHA expression in Y-79 ( Cat # L042V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

BCKDHA antibody

Western Blot analysis of BCKDHA expression in transfected 293T cell line (H00000593-T01) by BCKDHA MaxPab polyclonal antibody.

Lane 1: BCKDHA transfected lysate(48.95 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

BCKDHA antibody

Western Blot analysis of BCKDHA expression in transfected 293T cell line (H00000593-T01) by BCKDHA MaxPab polyclonal antibody.

Lane 1: BCKDHA transfected lysate(48.95 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

BCKDHA antibody

Human Lung Tissue; Rabbit Anti-BCKDHA Antibody . Catalog Number: ARP56119_P050 . Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue . Observed Staining: Cytoplasmic in alveolar type I & II cells . Primary Antibody Concentration: 1:100 . Secondary Antibody: Donkey anti-Rabbit-Cy3 . Secondary Antibody Concentration: 1:200 . Magnification: 20X . Exposure Time: 0.5 - 2.0 sec .; Rabbit Anti-BCKDHA Antibody (ARP56119_P050) ) in Human Lung Tissue using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

BCKDHA antibody

BCKDHA Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt, Ze WB
50 µg / €440.00
  Novus Biologicals Inc.

BCKDHA antibody

Immunohistochemistry-Paraffin: BCKDHA Antibody [NBP1-81022] - Immunohistochemical staining of human kidney shows strong granular positivity in cells in tubules. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

BCKDHA (46-445, His-tag)

BCKDHA Human Purified > 80 % E. coli
50 µg / €750.00
  Acris Antibodies GmbH

BCKDHA (46-445, His-tag)

BCKDHA Human Purified > 80 % E. coli
10 µg / €300.00
  Acris Antibodies GmbH

BCKDHA

BCKDHA Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

BCKDHA

BCKDHA Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

BCKDHA

BCKDHA Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

BCKDHA

BCKDHA Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

BCKDHA

BCKDHA Human Purified
10 µg / €380.00
  Novus Biologicals Inc.

BCKDHA

BCKDHA Human Purified
50 µg / €870.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

BCKDHA 293T Cell Transient Overexpression Lysate(Denatured)

BCKDHA 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

17 Item(s)

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