Bcl-11B antibody

Principal name

Bcl-11B antibody

Alternative names for Bcl-11B antibody

CTIP2, RIT1, BCL11B, B-cell lymphoma/leukemia 11B, B-cell CLL/lymphoma 11B, Radiation-induced tumor suppressor gene 1 protein, COUP-TF-interacting protein 2

SwissProt ID

Q99PV8 (Mouse), Q9C0K0 (Human)

Gene ID

64919 (BCL11B), 58208 (Bcl11b)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Mouse, Rat

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Enzyme Immunoassay (E), ChIP assay (ChIP), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Bcl-11B antibody

The transcription factor Bcl11b is expressed in thymus, mainly T cells. It is indispensable for T lineage development. When Bcl11b was deleted, T cells from all developmental stages acquired NK cell properties and concomitantly lost or decreased T cell-associated gene expression. These induced T-to-natural killer (ITNK) cells, which were morphologically and genetically similar to conventional NK cells, killed tumor cells in vitro, and effectively prevented tumor metastasis in vivo. Therefore, ITNKs may represent a new cell source for cell-based therapies. 
Structure: 894 amino acids with molecular weight of 96 kD. It encodes a C2H2-type zinc finger protein and is closely related to BCL11A.
Distribution: Nucleus.
Function: Tumor-suppressor protein involved in T-cell lymphomas. A key regulator of both differentiation and survival during thymocyte development.
Interaction: Interacts with TFCOUP1, SIRT1, ARP1, and EAR2.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Bcl-11B antibody

  Rat Monoclonal anti-Bcl11b Antibody  
Jurkat cell extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with anti-CTIP2 antibody (clone 25B6). Proteins were visualized using a goat anti-rat-IgG secodary conjugated to HRP and chemiluminescence detection. Rat IgG 25B6 Purified Hu, Ms, Ze ChIP, ICC/IF, P, WB
25 µg / €325.00
  OriGene Technologies, Inc.

Bcl-11B antibody

  Rabbit Polyclonal Anti-BCL11B Antibody  
WB Suggested Anti-BCL11B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Bcl-11B antibody

  Rabbit Polyclonal Anti-BCL11B Antibody  
WB Suggested Anti-BCL11B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Jurkat cell lysate; BCL11B is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Bcl-11B (Center) antibody

BCL11B Antibody (Center) (Cat. #AP50356PU-N) western blot analysis in K562 cell line lysates (35µg/lane).This demonstrates the BCL11B antibody detected the BCL11B protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Bcl-11B antibody

Bcl-11B Rabbit Aff - Purified Hu C, E, WB
25 µg / €430.00
  Acris Antibodies GmbH

Bcl-11B antibody

Bcl-11B Rabbit Purified Hu C, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

BCL11B - human gene knockout kit via CRISPR

BCL11B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

BCL11B - human gene knockout kit via CRISPR

BCL11B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

BCL11B - human gene knockout kit via CRISPR

BCL11B - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

BCL11B - human gene knockout kit via CRISPR

BCL11B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bcl11b - mouse gene knockout kit via CRISPR

Bcl11b - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Bcl11b - mouse gene knockout kit via CRISPR

Bcl11b - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bcl11b - mouse gene knockout kit via CRISPR

Bcl11b - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bcl11b - mouse gene knockout kit via CRISPR

Bcl11b - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BCL11B (mGFP-tagged) - Human B-cell CLL/lymphoma 11B (zinc finger protein) (BCL11B), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, BCL11B (mGFP-tagged) - Human B-cell CLL/lymphoma 11B (zinc finger protein) (BCL11B), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,880.00
  OriGene Technologies, Inc.

Lenti ORF particles, BCL11B (Myc-DDK tagged) - Human B-cell CLL/lymphoma 11B (zinc finger protein) (BCL11B), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, BCL11B (Myc-DDK tagged) - Human B-cell CLL/lymphoma 11B (zinc finger protein) (BCL11B), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €1,690.00
  OriGene Technologies, Inc.

16 Item(s)

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