Bcl-2-like 1 antibody

Principal name

Bcl-2-like 1 antibody

Alternative names for Bcl-2-like 1 antibody

Bcl2-L-1, BCL2L1, BCL2L, BCLX, Bcl-x, bcl-xL, bcl-xS, Bcl-2-like protein 1

SwissProt ID

O77737 (Pig), P53563 (Rat), Q07816 (Chick), Q07817 (Human), Q07817-1, Q64373 (Mouse)

Gene ID

598 (BCL2L1), 842598 (ACS10), 12048 (Bcl2l1), 561740

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), Rb (Rabbit), Fe (Feline), Sh (Sheep), Hst (Hamster), Mky (Monkey)

Available hosts

Rabbit, Mouse, Chicken, Sheep

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Flow Cytometry (F), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of Bcl-2-like 1 antibody

The Bcl-2 family of apoptosis-related genes plays central roles in regulating apoptotic pathways (reviewed in Thomadaki and Scorilas, 2006). Regulation of cell death through apoptosis is critical for the maintenance of homeostasis, defense against infectious agents, and normal development. Bcl-2 family proteins regulate apoptosis primarily through the regulation of mitochondrial outer membrane permeability. In mammals, the family consists of both prosurvival (antiapoptotic) and proapoptotic (prodeath) members. Cellular homeostasis is thought to be dependent on a balance between the actions of prosurvival and proapoptotic proteins. Bcl-2 family proteins can be divided into 3 main subfamilies on the basis of their function and the content of their Bcl-2 homology (BH) domains, for example: 1) Prosurvival: Bcl-2, Bcl-XL, Bcl-W, A1, and Mcl-1 2) Proapoptotic (multidomain): Bax, Bak, and Bok. 3) BH3-only (proapoptotic): Bad, Bcl-XS, Bid, Bik, Bim, Blk, Bmf, Bnip, Noxa, and Puma. Prosurvival members inhibit cells from undergoing apoptosis, whereas proapoptotic and BH3-only subfamily members promote apoptosis. There are 4 BH domains (1-4) conserved among Bcl-2 family proteins. The BH domains are important for function as well as for heterodimerization between family members. Typical prosurvival family members have all four BH domains (1-4), whereas proapoptotic (multidomain) members have BH1, 2 and 3 domains and BH3-only members have only the BH3 domain. Overall, the relative ratio of prosurvival and proapoptotic proteins determines the suseptibility of a cell to various apoptotic stimuli. Many Bcl-2 family proteins are differentially expressed in various malignancies and some are useful prognostic biomarkers. Prosurvival proteins are often elevated in diverse cancers and have the potential to confer resistance to both endogenous cell death stimuli and cancer treatments. Alterations in the ratio or levels of Bcl-2 family proteins have been also associated with nonmalignant diseases including neurodegenerative diseases, autoimmune diseases, AIDs, Down's syndrome, cardiovascular diseases, diabetes, glomerulonephritis, and muscular dystrophy. IMG-5691 recognizes Bcl-XL and Bcl-XS. Human Bcl-XL is a 233 amino acid protein; GenBank no. CAA80661.1. Human Bcl-XS is a 170 amino acid protein; GenBank no. CAA80662.1.

General readings

Basu A, et.al.( 2003) Mar 13; 538(1-3): 41-7
Cheng E.H.-Y. et.al. (1996) Nature 379:554-556.
Sattler M. et.al. (1997), Science 275:983-986.
Muchmore S.W.et.al (1996).Nature 381:335-341
Yu J., Zhang L. Mol. (2001)Cell 7:673-682

  1. Quick-Filters:
  2. Highly Validated (5)

Items 1 to 20 of 113 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Bcl-2-like 1 antibody

Sample (30 ug of whole cell lysate). . A:NIH-3T3. 12% SDS PAGE. . TA308852 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 1 antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-BCL-XL mouse monoclonal antibody. (TA500097) Mouse IgG2a OTI4A9 Purified Hu ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Bcl-2-like 1 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-BCL2L1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506188) Mouse IgG1 OTI2D1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Bcl-2-like 1 antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between BCL2L1 and BAX. HeLa cells were stained with anti-BCL2L1 rabbit purified polyclonal 1:1200 and anti-BAX mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Bcl-2-like 1 antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between BID and BCL2L1. HeLa cells were stained with anti-BID rabbit purified polyclonal 1:1200 and anti-BCL2L1 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Mouse IgG1 3E2-2A5 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Bcl-2-like 1 antibody

Human Hodgkin’s lymphoma stained with Anti-Bcl-xL Mouse 7D9/SPM519 Purified Hu, Ms P
0.5 ml / €360.00
  Acris Antibodies GmbH

Bcl-2-like 1 antibody

Human Hodgkin’s lymphoma stained with Anti-Bcl-xL Mouse 7D9/SPM519 Purified Hu, Ms P
1 ml / €500.00
  Acris Antibodies GmbH

Bcl-2-like 1 antibody

Human Hodgkin’s lymphoma stained with Anti-Bcl-xL Mouse 7D9/SPM519 Purified Hu, Ms P
0.1 ml / €190.00
  Acris Antibodies GmbH

Bcl-2-like 1 (1-50) antibody

Formalin-Fixed, Paraffin-Embedded Hodgkin's lymphoma stained with Bcl-X Antibody Cat.-No AP32834PU (Clone BX006). Note cytoplasmic and membrane staining. Mouse IgG2a BX006 Purified Hu, Ms, Por, Rt C, F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Bcl-2-like 1 (1-50) antibody

Formalin-Fixed, Paraffin-Embedded Hodgkin's lymphoma stained with Bcl-X Antibody Cat.-No AP32834PU (Clone BX006). Note cytoplasmic and membrane staining. Mouse IgG2a BX006 Purified Hu, Ms, Por, Rt C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Bcl-2-like 1 (1-50) antibody

Formalin-Fixed, Paraffin-Embedded Hodgkin's lymphoma stained with Bcl-X Antibody Cat.-No AP32834PU (Clone BX006). Note cytoplasmic and membrane staining. Mouse IgG2a BX006 Purified Hu, Ms, Por, Rt C, F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Bcl-2-like 1 antibody

Formalin-Paraffin Hodgkin's lymphoma stained with Bcl-X Antibody Cat.-No AM33365PU (Clone 2H12). Note cytoplasmic and membrane staining. Mouse IgG2a 2H12 Purified Hu, Ms, Por, Rt C, F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Bcl-2-like 1 antibody

Formalin-Paraffin Hodgkin's lymphoma stained with Bcl-X Antibody Cat.-No AM33365PU (Clone 2H12). Note cytoplasmic and membrane staining. Mouse IgG2a 2H12 Purified Hu, Ms, Por, Rt C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Bcl-2-like 1 antibody

Formalin-Paraffin Hodgkin's lymphoma stained with Bcl-X Antibody Cat.-No AM33365PU (Clone 2H12). Note cytoplasmic and membrane staining. Mouse IgG2a 2H12 Purified Hu, Ms, Por, Rt C, F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Bcl-2-like 1 antibody

Formalin-paraffin Hodgkin's lymphoma stained with Bcl-x Antibody Cat.-No AM50165PU (Clone SPM165). Note cytoplasmic and membrane staining. Mouse IgG2a SPM165 Purified Hu, Ms, Por, Rt C, F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Bcl-2-like 1 antibody

Formalin-paraffin Hodgkin's lymphoma stained with Bcl-x Antibody Cat.-No AM50165PU (Clone SPM165). Note cytoplasmic and membrane staining. Mouse IgG2a SPM165 Purified Hu, Ms, Por, Rt C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Bcl-2-like 1 antibody

Formalin-paraffin Hodgkin's lymphoma stained with Bcl-x Antibody Cat.-No AM50165PU (Clone SPM165). Note cytoplasmic and membrane staining. Mouse IgG2a SPM165 Purified Hu, Ms, Por, Rt C, F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Bcl-2-like 1 antibody

Formalin-Paraffin Hodgkin's lymphoma stained with Bcl-X Antibody Cat.-No AM50202PU (Clone BX006 + 2H12). Note cytoplasmic and membrane staining. Mouse IgG2a BX006 + 2H12 Purified Hu, Ms, Por, Rt C, F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Bcl-2-like 1 antibody

Formalin-Paraffin Hodgkin's lymphoma stained with Bcl-X Antibody Cat.-No AM50202PU (Clone BX006 + 2H12). Note cytoplasmic and membrane staining. Mouse IgG2a BX006 + 2H12 Purified Hu, Ms, Por, Rt C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Bcl-2-like 1 antibody

Formalin-Paraffin Hodgkin's lymphoma stained with Bcl-X Antibody Cat.-No AM50202PU (Clone BX006 + 2H12). Note cytoplasmic and membrane staining. Mouse IgG2a BX006 + 2H12 Purified Hu, Ms, Por, Rt C, F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Items 1 to 20 of 113 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  • LinkedIn