Bcl-2-like 14 antibody

Principal name

Bcl-2-like 14 antibody

Alternative names for Bcl-2-like 14 antibody

Bcl-G, Bcl2-L-14, BCLG, BCL2L14, Apoptosis facilitator Bcl-2-like protein 14

SwissProt ID

Q5E9L4 (Bovin), Q6AYK4 (Rat), Q9BZR8 (Human), Q9CPT0 (Mouse)

Gene ID

79370 (BCL2L14), 66813 (Bcl2l14), 500348

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), EPair for Elisa (EPair)

Background of Bcl-2-like 14 antibody

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain (reviewed in 1 and 2). BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bcl-G (3). The mRNA of Bcl-G encodes 2 isoforms, Bcl-GL, which is widely expressed in multiple tissues, and Bcl-GS, which is only found in testis. The Bcl-GS protein is predominantly localized to cytoplasmic organelles whereas Bcl-GL was distributed throughout the cytosol. Overexpression of either protein induced apoptosis, although Bcl-GS was far more potent than Bcl-GS. Apoptosis induction was dependent on the BH3 domain and could be suppressed by co-expression with the anti-apoptotic Bcl-XL protein (3).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Bcl-2-like 14 (C-term) antibody

  Rabbit Polyclonal Bcl-G Antibody  
Western blot analysis of Bcl-G in U937 cell lysates with Bcl-G antibody at (A) 2.5 and (B) 5 ug/ml. Rabbit Purified Hu, Ms, Rt E, P, WB
0.1 mg / €371.00
  OriGene Technologies, Inc.

Bcl-2-like 14 (C-term) antibody

Pancreas: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt P, WB
50 µg / €380.00
  OriGene Technologies GmbH

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