Bcl-2-like 7 antibody

Principal name

Bcl-2-like 7 antibody

Alternative names for Bcl-2-like 7 antibody

BAK1, BAK, BCL2L7, Bcl2-L-7, CDN1, Bcl-2 homologous antagonist/killer, Apoptosis regulator BAK, Bcl-2-like protein 7, cell death inhibitor 1

SwissProt ID

O08734 (Mouse), Q16611 (Human)

Gene ID

578 (BAK1)

Available reactivities

Hu (Human), Ms (Mouse), Hst (Hamster), Rt (Rat), Por (Porcine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of Bcl-2-like 7 antibody

BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

General readings

Birgit Kemmerling, et al. (2008) Plant Signal Behav, 3(2): 116–118.
Libo Shan, et al. (2008) Cell Host Microbe, 4(1): 17–27.
Xu-Bao Shi, et al. (2007) Proc Natl Acad Sci U S A, 104(50): 19983–19988.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Bcl-2-like 7 (1-14) antibody

Human Lung, respiratory epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Bcl-2-like 7 (N-term) antibody

  Goat Polyclonal Antibody against BAK1  
TA302647 staining (0.5µg/ml) of A431 lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 7 (N-term) antibody

  Rabbit Polyclonal Bak Antibody  
Western blot analysis of Bak in L1210 cell lysates with Bak antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 7 antibody

  Rabbit polyclonal anti-BAK1/BAK antibody  
Western blot analysis of extracts from 293 cells, using Bak antibody (#TA311844).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 7 antibody

  Anti-BAK1 rabbit polyclonal antibody  
Predicted band size: 23kDa. Positive control: Hela, A431, 293T and Jurkat cell lysate. Recommended dilution: 1/1000-5000. (Gel: 12%SDS-PAGE Lane1-4: Hela, A431, 293T and Jurkat cell lysate Lysates: 40 ug per lane Primary antibody: 1/900 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 5 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 7 antibody

  Rabbit anti-BAK1 Polyclonal Antibody  
Western blot analysis of extracts of MCF7 cell lines, using BAK1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 7 antibody

  Rabbit Polyclonal Anti-BAK1 Antibody  
WB Suggested Anti-BAK1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Muscle Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 7 antibody

  Rabbit Polyclonal Anti-Bak Antibody  
Western blot analysis on 293 cell lysate using Bak Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 7 antibody

Immunofluorescence of human HeLa cells stained with Hoechst 3342 (Blue) for nucleus staining and monoclonal anti-human BAK1 antibody (1:500) with Texas Red (Red). Mouse IgG2a AT8B4 Purified Hu, Ms E, F, ICC/IF, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

Bcl-2-like 7 antibody

Immunofluorescence of human HeLa cells stained with Hoechst 3342 (Blue) for nucleus staining and monoclonal anti-human BAK1 antibody (1:500) with Texas Red (Red). Mouse IgG2a AT8B4 Purified Hu, Ms E, F, ICC/IF, WB
50 µl / €230.00
  Acris Antibodies GmbH

Bcl-2-like 7 antibody

Immunohistochemistry (IHC) analyzes of Bak1/2 antibody (Cat.-No.: AP06026PU-N) in paraffin-embedded human skeletal muscle tissue. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Bcl-2-like 7 (BH3 Domain) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Bcl-2-like 7 (N-term) antibody

Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with BAK1 antibody AP22701PU-N at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Purified Hst, Hu, Ms P
0.25 ml / €470.00
  Acris Antibodies GmbH

Bcl-2-like 7 antibody

Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using Bak Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
50 µg / €230.00
  Assay Biotech

Bcl-2-like 7 antibody

Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using Bak Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

BAK1 - human gene knockout kit via CRISPR

BAK1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

BAK1 - human gene knockout kit via CRISPR

BAK1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

BAK1 - human gene knockout kit via CRISPR

BAK1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

BAK1 - human gene knockout kit via CRISPR

BAK1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

BAK1 overexpression lysate

BAK1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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