Bcl-2-like 8 antibody

Principal name

Bcl-2-like 8 antibody

Alternative names for Bcl-2-like 8 antibody

BAD, BBC6, BCL2L8, Bcl-2-like protein 8, Bcl2-L-8, Bcl2 antagonist of cell death, Bcl-2-binding component 6, Bcl-XL/Bcl-2-associated death promoter

SwissProt ID

O35147 (Rat), Q61337 (Mouse), Q92934 (Human)

Gene ID

572 (BAD), 12015 (Bad), 64639

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Bov (Bovine), Can (Canine)

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Flow Cytometry (F), ELISA (detection) (E(detection)), Dot blot (Dot)

Background of Bcl-2-like 8 antibody

Apoptosis or programmed cell death is a physiological cellular process characterized by cell shrinkage, membrane blebbing, DNA fragmentation, and release of Cytochrome C from the mitochondria. It is utilized by the organism to get rid of unwanted cells, which is critical for normal development and homeostasis of an organism. Disregulation of normal apoptosis process have been implicated in a variety of diseases, including cancer, autoimmune diseases, viral infections, etc. Programmed cell death occurs through complex cascades of cell signaling in which Bcl-2 family members, among others, play an important role.The Bcl-2 family of proteins regulate apoptosis as well as execute death signals at the mitochondrion. Members of this family include both pro- and anti-apoptotic proteins that hare homology sequences called Bcl-2 Homology domains (BH1-4) which mediate dimmer formation. The BH3 proteins, such as BID, NOXA, PUMA, BIK, BIM and BAD are all pro-apoptotic and share sequence homology within the amphipathic alpha-helical BH3 region, which is required for their apoptotic function. They may trigger release of death-inducing molecules such as Cytochrome C, Smac, and endonuclease G. Anti-apoptotic family members, including Bcl-2 and Bcl-XL, play inhibitory roles. Bcl-2 family proteins may form homodimers or heterodimers between pro- and anti-apoptotic members, the ratios of which determine the cell fate.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Bcl-2-like 8 antibody

Western blot analysis of Bad in T24 cell lysates with Bad antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 8 antibody

Western blot analysis of extracts from 293 cells, treated with Etoposide (25uM, 60mins), using BAD (Cleaved-Asp71) antibody (#TA312433).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 8 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using BAD antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 8 (Center) antibody

Western blot analysis of anti-Bad Antibody (Center)(Cat.#TA324511) in HL60 cell line lysates (35ug/lane). Bad(arrow) was detected using the purified Pab. Rabbit Aff - Purified Hu P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 8 (BH3 Domain) antibody

Western blot analysis of Bad BH3 Domain antibody (Cat.# TA324514) in mouse bladder tissue lysates (35ug/lane). Bad (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu F, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 8 antibody

Western blot analysis of BAD expression in Forskolin treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 8 antibody

Western blot analysis of BAD expression in Forskolin treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 8 antibody

Western Blot: cleaved BAD Antibody [NB100-56602] - Western blot analysis of Bad-cv using NB100-56602 at 1:500 against lysate of (A) untreated HeLa cells and (B) HeLa cells treated with TNFa for 2 hrs. Rabbit Purified Hu F, WB
0.2 ml / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 8 antibody

ELISA: Bad Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

Bcl-2-like 8 antibody

Bcl-2-like 8 Mouse IgG1 5E6 Purified Hu ICC/IF, IP, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

Bcl-2-like 8 pSer155/118 antibody

Figure 1. Western analysis of cell extracts from 293 cells transfected with Flag-Bad, using Phospho-mBad-Ser155 Antibody (Cat #AM11017PU-N). Mouse IgG1 27AT381 Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Bcl-2-like 8 pSer155/118 antibody

Bcl-2-like 8 Mouse IgG1 27AT937 Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Bcl-2-like 8 antibody

Bcl-2-like 8 Rabbit Aff - Purified Hu, Ms, Rt IP, P, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

Bcl-2-like 8 pSer112/75 antibody

Bcl-2-like 8 Rabbit Purified Hu, Ms, Rt IP, WB
0.1 mg / €460.00
  Acris Antibodies GmbH

Bcl-2-like 8 pSer136/99 antibody

Bcl-2-like 8 Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Bcl-2-like 8 pSer155/118 antibody

Bcl-2-like 8 Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Bcl-2-like 8 pSer112/75 antibody

Immunohistochemistry (IHC) analyzes of BAD pSer112 antibody (Cat.-No.: AP01734PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Bcl-2-like 8 pSer112/75 antibody

Figure 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BAD (phospho-Ser112) antibody AP02366PU. Rabbit Aff - Purified Hu, Ms P, WB
0.1 ml / €320.00
  Acris Antibodies GmbH

Bcl-2-like 8 pSer112/75 antibody

Figure 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BAD (phospho-Ser112) antibody AP02366PU. Rabbit Aff - Purified Hu, Ms P, WB
50 µl / €240.00
  Acris Antibodies GmbH

Bcl-2-like 8 antibody

Immunohistochemical analysis of paraffin- embedded human breast carcinoma tissue using BAD antibody. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €270.00
  Acris Antibodies GmbH

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