Bcl-3 antibody

Principal name

Bcl-3 antibody

Alternative names for Bcl-3 antibody

BCL3, BCL4, D19S37, B-cell lymphoma 3-encoded protein

SwissProt ID

P20749 (Human), Q9Z2F6 (Mouse)

Gene ID

602 (BCL3), 12051 (Bcl3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Hamster, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of Bcl-3 antibody

The Ham150-3.5 antibody reacts with mouse and human Bcl-3. Bcl-3 is a member of the IkappaB multigene family, which modulates the activities of NF-kappaB/Rel transcription factors. Bcl-3 is reported to increase transcription from NF-kappaB responsible promoters and to dissociate p50-p52 homodimers from DNA. Bcl-3 is phosphorylated influencing its interaction with both p50 and p52. Bcl-3 was cloned from a chromosomal breakpoint in the t(14;19) translocation, which is found in some cases of chronic B-cell lymphocytic leukemias. Bcl-3 is required for T-cell-dependent immunity. Bcl-3-deficient mice are defective in antigen-specific antibody production and germinal-center formation and fail to resist infection. Bcl-3 may also contribute to B-cell survival, which may explain its oncogenic potential when expressed at high levels as result of chromosomal translocation. Bcl-3 is detected in different tissues, especially the spleen and other lymphoid organs. The gene was shown to be induced by mitogenic stimuli in B and T cells and by cytokines on human erythroid precursors. It is shown that Bcl-3 expression is able to block apoptosis in IL-4-deprived cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Bcl-3 (Center) antibody

Formalin-fixed and paraffin-embedded human lung carcinoma reacted with BCL3 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu, Ms F, ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Bcl-3 antibody

Western blot analysis of Jurkat cells (Lane 1: 20ug and Lane 2: 40ug cell lysate) with anti-BCL3 antibody. Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Bcl-3 antibody

Western blot analysis of BCL3 in 293 cell lysate with BCL3 antibody at 1 ug/mL. Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Bcl-3 antibody

Bcl-3 Hamster IgG1 Ham150-3.5 Biotin Hu, Ms E
0.3 mg / €480.00
  Acris Antibodies GmbH

Bcl-3 antibody

Bcl-3 Hamster IgG1 Ham150-3.5 Biotin Hu, Ms E
0.1 mg / €260.00
  Acris Antibodies GmbH

Bcl-3 antibody

Bcl-3 Hamster IgG1 Ham150-3.5 FITC Hu, Ms F
0.3 mg / €480.00
  Acris Antibodies GmbH

Bcl-3 antibody

Bcl-3 Hamster IgG1 Ham150-3.5 FITC Hu, Ms F
0.1 mg / €280.00
  Acris Antibodies GmbH

Bcl-3 antibody

Western Blot Analysis of AM31856PU-N bcl-3 antibody:  Lysate from Mouse Spleen and Thymus (Thymus shown above) cells probed with AM31856PU-N
at 1.0 µg/ml. AP conjugated Goat Anti-Hamster IgG as secondary antibody. Hamster IgG1 Ham150-3.5 Purified Hu, Ms E, F, WB
0.25 mg / €370.00
  Acris Antibodies GmbH

Bcl-3 antibody

Bcl-3 Hamster IgG1 Ham150-3.5 PE Hu, Ms F
0.3 mg / €550.00
  Acris Antibodies GmbH

Bcl-3 antibody

Bcl-3 Hamster IgG1 Ham150-3.5 PE Hu, Ms F
50 µg / €240.00
  Acris Antibodies GmbH

Bcl-3 antibody

Western blot analysis of Bcl-3 in Jurkat cell lysate using antibody AP00151PU-N Rabbit Aff - Purified Hu, Ms, Rt IP, P, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

Bcl-3 antibody

Immunofluorescence of purified MaxPab antibody to BCL3 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

Bcl-3 antibody

Immunoprecipitation of BCL3 transfected lysate using anti-BCL3 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with BCL3 MaxPab mouse polyclonal antibody (B01) (H00000602-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

Bcl-3 antibody

Western Blot analysis of BCL3 expression in transfected 293T cell line (H00000602-T02) by BCL3 MaxPab polyclonal antibody.

Lane 1: BCL3 transfected lysate(46.80 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Bcl-3 antibody

Bcl-3 Hamster IgG 150-3.5 Hu, Ms E, WB
0.1 mg / €510.00
  Abnova Taiwan Corp.

Bcl-3 antibody

Bcl-3 Hamster IgG B325H Purified Hu, Ms E, WB
0.1 mg / €640.00
  Abnova Taiwan Corp.

Bcl-3 antibody

Western blot analysis of BCL3 expression in Jurkat cell lysate. Rabbit Hu, Ms, Rt C, IP, WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

Bcl-3 antibody

Bcl-3 Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

Bcl-3 antibody

Bcl-3 protein detected in transfected 293 cell lysates. Hamster IgG1 HAM150-3.5 Ascites Ms C, WB
0.1 ml / €370.00
  Neuromics Antibodies

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Bcl-3

Bcl-3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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