BDKRB1 antibody

Principal name

BDKRB1 antibody

Alternative names for BDKRB1 antibody

BRADYB1, BKB1R, BKR1, B1 bradykinin receptor, Bradykinin B1 Receptor, BK-1 receptor, B1R

SwissProt ID

P46663 (Human), P97583 (Rat), Q61125 (Mouse), Q8HZN9 (Pig), Q9BDQ5 (Canfa)

Gene ID

623 (BDKRB1), 81509 (Bdkrb1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Por (Porcine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Paraffin Sections (P), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), EPair for Elisa (EPair)

Background of BDKRB1 antibody

Kinins are small peptides rapidly produced following tissue injury that serve as important modulators of inflammation and pain. In the periphery, the actions of kinins include vasodilatation, increased vascular permeability, stimulation of immune cells, and induction of pain. Kinins in the central nervous system (CNS) appear to initiate a similar cascade of events leading to neural tissue damage as well as long lasting disturbances affecting blood-brain barrier function. Kinins such as Bradykinin (BK), Lys-BK, desArg-BK, and Lys-desArg-BK exert their action via two distinct receptors: the B1 Bradykinin receptor (BKRB1) and the B2 Bradykinin receptor (BKRB2). The desArg9-BK and Lys-desArg9-BK peptides activate BKRB1 while BK and Lys-BK operate by activating BKRB2. Both BKRB1 and BKRB2 are members of the seven-transmembrane domain, G protein-coupled receptor (GPCR) superfamily and share a common structure of seven putative transmembrane domains, an extracellular amino terminus, and a cytoplasmic carboxyl terminus. Expression of BKRB1is inducible upon various types of tissue injury and by inflammatory mediators such as bacterial lipopolysaccharide (LPS) and cytokines. BKRB1 was long considered not to be expressed in healthy tissues. However, recent work has demonstrated a low level of expression of BKRB1 in the CNS of rodent and primates. In contrast, BKRB2 is constitutively expressed on various cell types. BKRB1 represents a potential therapeutic target for treatment of inflammatory disorders and cardiovascular diseases.

General readings

Bengtson SH, Eddleston J, Christiansen SC, Zuraw BL.
Double-stranded RNA increases kinin B1 receptor expression and function in human airway epithelial cells.
Int Immunopharmacol. 2007 Dec 20;7(14):1880-7. Epub 2007 Jul 30
PMID: 18039525

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BDKRB1 (Center) antibody

TA302436 (2µg/ml) staining of K562 lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BDKRB1 (Cytopl. Dom.) antibody

Anti-B1R / BDKRB1 antibody IHC of human artery, smooth muscle, atherosclerosis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml. Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €345.00
  OriGene Technologies, Inc.

BDKRB1 (2nd Extracell. Dom.) antibody

Anti-BDKRB1 antibody IHC of human smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Hu, Mky P
50 µg / €345.00
  OriGene Technologies, Inc.

BDKRB1 (3rd Intracell. Loop) antibody

Western blot analysis of rat brain (1,3) and rat heart (2,4) lysates: 1. Anti-B1 Bradykinin Receptor antibody, (1:200). 2. Anti-B1 Bradykinin Receptor antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt C, WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

BDKRB1 (C-term) antibody

Host: Rabbit; Target Name: BDKRB1; Sample Tissue: THP-1 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

BDKRB1 (Center) antibody

Western blot (WB) analysis of Bradykinin B1 R antibody (Cat.-No.: AP01308PU-N) in extracts from K562 cells. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

BDKRB1 (Center) antibody

Western blot analysis of BDKRB1 Antibody (Center) (AP17901PU-N) in HepG2 cell line lysates (35ug/lane). BDKRB1 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BDKRB1 (C-term) antibody

Immunohistochemical staining of Human Vascular Smooth Muscle Ssections using anti-BDKRB1 antibody SP4076P (Formalin-Fixed Paraffin Embedded). Rabbit Aff - Purified Bear, Bov, Eq, Hu, Mky, Por, Prim P
50 µg / €470.00
  Acris Antibodies GmbH

BDKRB1 antibody

BDKRB1 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

BDKRB1 antibody

Western Blot analysis of BDKRB1 expression in transfected 293T cell line (H00000623-T02) by BDKRB1 MaxPab polyclonal antibody.

Lane 1: BDKRB1 transfected lysate(38.83 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

BDKRB1 antibody

Western Blot analysis of BDKRB1 expression in transfected 293T cell line (H00000623-T02) by BDKRB1 MaxPab polyclonal antibody.

Lane 1: BDKRB1 transfected lysate(38.83 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

BDKRB1 antibody

Western Blot analysis of BDKRB1 expression in transfected 293T cell line (H00000623-T03) by BDKRB1 MaxPab polyclonal antibody.

Lane 1: BDKRB1 transfected lysate(38.94 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

BDKRB1 antibody

BDKRB1 Mouse IgG2a 3A2 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

BDKRB1 antibody

BDKRB1 polyclonal antibody ( Cat # PAB7493 ) ( 2 µg/ml ) staining of K-562 lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

BDKRB1 antibody

Immunofluorescence analysis of LOVO cells, using BDKRB1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

BDKRB1 antibody

Immunofluorescence analysis of LOVO cells, using BDKRB1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

BDKRB1 antibody

Western blot analysis of BDKRB1 expression in Saos2 (A); SW837 (B) whole cell lysates. Rabbit Aff - Purified Hu ICC/IF, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

BDKRB1 antibody

Western blot analysis of BDKRB1 expression in Saos2 (A); SW837 (B) whole cell lysates. Rabbit Aff - Purified Hu ICC/IF, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

BDKRB1 antibody

Western blot analysis of BDKRB1 expression in Saos2 (A); SW837 (B) whole cell lysates. Rabbit Aff - Purified Hu ICC/IF, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

BDKRB1 antibody

NB100-96919(2ug/ml) staining of K562 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

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