BDKRB2 antibody

Principal name

BDKRB2 antibody

Alternative names for BDKRB2 antibody

B2 bradykinin receptor, BKR2, BK-2 receptor, B2R, B1BKR

SwissProt ID

P25023 (Rat), P30411 (Human), P32299 (Mouse), Q9GLX8 (Pig)

Gene ID

624 (BDKRB2), 25245 (Bdkrb2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Flow Cytometry (F), Immunoprecipitation (IP)

Background of BDKRB2 antibody

Kinins are small peptides produced rapidly following tissue injury that serve as important modulators of inflammation and pain. In the periphery, the actions of kinins include vasodilatation, increased vascular permeability, stimulation of immune cells, and induction of pain. Kinins in the central nervous system (CNS) seem to initiate a similar cascade of events leading to neural tissue damage, as well as long lasting disturbances affecting blood-brain barrier function. Kinins, such as Bradykinin (BK), Lys-BK, desArg-BK, and Lys-desArg-BK, exert their action via two distinct receptors: the B1 Bradykinin receptor (BKRB1) and the B2 Bradykinin receptor (BKRB2). BKRB2 is activated by BK and Lys-BK while desArg-BK and Lys-desArg-BK activate BKRB1. Activation of BKRB2 liberates mediators of vascular tone, fibrinolysis, and pain. BKRB2, which mediates most of the physiological effects of kinins, as well as BKRB1, represent potential therapeutic targets for treatment of inflammatory disorders and cardiovascular diseases. Both BKRB1 and BKRB2 are members of the seven-transmembrane domain, G protein-coupled receptor (GPCR) superfamily and share a common structure of seven putative transmembrane domains, an extracellular amino terminus, and a cytoplasmic carboxy terminus. BKRB2 is constitutively and widely expressed throughout the CNS and peripheral nervous system and on various cell types including endothelial cells, nerve fibers, leukocytes, and mast cells.

General readings

Michineau,S., (2006) Biochemistry 45 (8), 2699-2707

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BDKRB2 (C-term) antibody

Formalin-Fixed, Paraffin-Embedded Human Brain, Neurons and Glia stained with BDKRB2 Antibody Cat.-No SP4078P after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Mky, Ms, Por, Prim ICC/IF, P
50 µg / €470.00
  Acris Antibodies GmbH

BDKRB2 antibody

Predicted band size: 44kDa. Positive control: Human leiomyosarcoma tissue and NIH/3T3 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: Human leiomyosarcoma tissue lysate Lane2: NIH/3T3 cell lysate Lysates: 50 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BDKRB2 antibody

Predicted band size: 45 kDa . Positive control: Jurkat cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 50 ug per lane Primary antibody: 1/800 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BDKRB2 antibody

Western blot analysis of rat brain lysate: 1. Anti-B2 Bradykinin Receptor antibody, (1:1000). 2. Anti-B2 Bradykinin Receptor antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt ICC/IF, WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

BDKRB2 antibody

Immunofluorescent detection of Bradykinin R2 in Rat brain using Cy3 conjugated anti-rabbit secondary antibodies (red fluorescence). Rabbit Serum Ms, Rt C, ICC/IF
0.1 ml / €270.00
  Acris Antibodies GmbH

BDKRB2 antibody

Human Jurkat; WB Suggested Anti-BDKRB2 Antibody Titration: 5.0ug/ml. Positive Control: Jurkat cell lysate; BDKRB2 antibody - N-terminal region (AP32713PU-N) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu WB
0.1 mg / €310.00
  Acris Antibodies GmbH

BDKRB2 antibody

BDKRB2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

BDKRB2 antibody

Detection limit for recombinant GST tagged BDKRB2 is approximately 0.1ng/ml as a capture antibody. Mouse IgG1 3F6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

BDKRB2 antibody

Human Jurkat; WB Suggested Anti-BDKRB2 Antibody Titration: 5.0ug/ml. Positive Control: Jurkat cell lysate; BDKRB2 antibody - N-terminal region (ARP41781_T100) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu WB
0.1 mg / €310.00
  AVIVA Systems Biology

BDKRB2 antibody

Immunofluorescent detection of Bradykinin R2 in rat brain using Cy3 conjugated anti-rabbit secondary antibodies (red fluorescence). Rabbit Serum Ms, Rt C, ICC/IF
0.1 ml / €270.00
  Neuromics Antibodies

BDKRB2 antibody

Immunohistochemistry-Paraffin: BDKRB2 Antibody [NBP1-46328] - Rat spinal cord (paraffin section) using Rabbit antibody to c-terminal region of BDKRB2 (B2 bradykinin receptor): whole serum at 1 : 200 dilution incubated overnight at room temperature, developed with DAB/Ni and counterstained with hem Rabbit Purified Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

BDKRB2 antibody

Western Blot: BDKRB2 Antibody [NBP1-59044] - This Anti-BDKRB2 antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 5ug/ml. Rabbit Purified Hu WB
0.1 mg / €360.00
  Novus Biologicals Inc.

BDKRB2 antibody

BDKRB2 Goat Purified Ms, Rt C, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

BDKRB2 antibody

Western Blot: BDKRB2 Antibody (EPR5646) [NBP1-95843] - SY5Y, (C) JAR, and (D) 293T cell lysates using anti-BDKRB2. Rabbit EPR5646 Purified Hu, Ms F, IP, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

BDKRB2

BDKRB2 Human
2 µg / €300.00
  Abnova Taiwan Corp.

BDKRB2

BDKRB2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

BDKRB2

BDKRB2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

17 Item(s)

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