Alternative names for BEAN1 antibody
Brain-expressed protein associating with Nedd4 homolog, BEAN
Western blot / Immunoblot (WB)
Background of BEAN1 antibody
The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Altertively spliced transcript variants encoding different isoforms have been found for this gene.