Beclin-1-like protein 1 antibody

Principal name

Beclin-1-like protein 1 antibody

Alternative names for Beclin-1-like protein 1 antibody

BECN1L1, Beclin 2

SwissProt ID

A8MW95 (Human)

Gene ID

596 (BCL2), 441925 (BECN1P1)

Ncbi ID


Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts


Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of Beclin-1-like protein 1 antibody

Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells (1,2). Beclin 2 is a mammalian specific homolog of the autophagy protein Beclin 1 (3). Like Beclin 1, Beclin 2 interacts with Bcl-2 and class III PI3K complex components. However, Beclin 2 functions in an additiol lysosomal degradation pathway and is required for ligand-induced endolysosomal degradation of several G protein-coupled receptors (3). Beclin 2 is also required for agonist-induced lysosome-mediated degradation of EGFR in lung cancer cells, suggesting that it may also play a role in regulating other intracellular sigling pathways (4).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Beclin-1-like protein 1 antibody

  Rabbit Polyclonal Anti-Beclin 2 Antibody  
Western blot analysis of Beclin 2 in Jurkat cell lysate with Beclin 2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Purified Hu ICC/IF, P, WB
0.1 mg / €382.00
  OriGene Technologies, Inc.

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