Beta-crystallin A3 antibody

Principal name

Beta-crystallin A3 antibody

Alternative names for Beta-crystallin A3 antibody


SwissProt ID

P02525 (Mouse), P05813 (Human), P10042 (Chick), P11843 (Bovin), P14881 (Rat)

Gene ID

1411 (CRYBA1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Beta-crystallin A3 antibody

Crystallins are the domint structural components of the vertebrate eye lens. Defects in CRYBA1 are the cause of congenital zonular cataract with sutural opacities (CCZS).Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-termil extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-termil extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mR, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alterte translation initiation site. Deletion of exons 3 and 4 causes the autosomal domint disease 'zonular cataract with sutural opacities'. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Beta-crystallin A3 antibody

  Rabbit Polyclonal Anti-CRYBA1 Antibody  
WB Suggested Anti-CRYBA1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: HT1080 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €360.00
  OriGene Technologies, Inc.

Beta-crystallin A3 (Center) antibody

Formalin fixed, paraffin embedded human cerebellum tissue stained with Beta-crystallin A3 Antibody Cat.-No AP51091PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €370.00
  OriGene Technologies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Beta-crystallin A3

  Recombinant protein of human crystallin, beta A1 (CRYBA1)  
Beta-crystallin A3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.


Catalog No.    

CRYBA1 overexpression lysate

CRYBA1 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

4 Item(s)

per page
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