Beta-glucuronidase antibody

Principal name

Beta-glucuronidase antibody

Alternative names for Beta-glucuronidase antibody

GUSB, Beta-G1

SwissProt ID

O18835 (Canfa), O97524 (Felca), P05804 (Ecoli), P06760 (Rat), P08236 (Human), P12265 (Mouse), Q4FAT7 (Pig)

Gene ID

946149 (uidA), 2990 (GUSB)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish), E. coli (Escherichia coli), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Dot blot (Dot), Immunodiffusion (ID), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Radioimmunoassay (R), Flow Cytometry (F), ELISA (detection) (E(detection))

Background of Beta-glucuronidase antibody

GUSB(Beta-Glucuronidase) is an enzyme that in humans is encoded by the GUSB gene. The GUSB gene encodes beta-glucuronidase, a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans. It is a tetrameric glycoprotein composed of identical subunits. The GUSB gene is mutated in mucopolysaccharidosis type VII. Miller et al. (1990) reported that the GUSB gene is 21 kb long and contains 12 exons. The GUSB gene is mapped on 7q11.21. Beta-glucuronic acid acts naturally to cleave glucuronides from conjugated bilirubin to produce unconjugated bilirubin, which is then absorbed into the bloodstream.Kreamer et al. (2001) postulated that the beta-glucuronidase inhibitor L-aspartic acid can thus block enterohepatic circulation of bilirubin. Tomatsu et al. (2002) stated that more than 45 different mutations in the GUSB gene had been identified in human patients with MPS VII, approximately 90% of which were point mutations.

General readings

Tomatsu,S. Hum. Mutat. 30 (4), 511-519 (2009)
Romanowski,T. Med. Sci. Monit. 14 (7), BR147-BR152 (2008)
Gratz,M. Pharmacogenet. Genomics 15 (12), 875-881 (2005)

20 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Beta-glucuronidase antibody

Western blot analysis of extracts from HeLa cells, using GUSB antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Beta-glucuronidase antibody

WB Suggested Anti-GUSB Antibody Titration: 2.5 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Rb P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Beta-glucuronidase antibody

Beta-glucuronidase Mouse IgG1 105 Supernatant Hu C, E, WB
1 ml / €360.00
  Acris Antibodies GmbH

Beta-glucuronidase antibody

Beta-glucuronidase Rabbit IgG Azide Free E. coli Dot, E, ICC/IF, ID, IP, R, WB
10 mg / €230.00
  Acris Antibodies GmbH

Beta-glucuronidase antibody

Beta-glucuronidase Rabbit IgG Biotin E. coli Dot, E, ICC/IF, ID, IP, R, WB
1 ml / €340.00
  Acris Antibodies GmbH

Beta-glucuronidase (Center) antibody

Immunohistochemistry analysis in formalin-fixed and paraffin-embedded human colon carcinoma reacted with Beta-glucuronidase Antibody (Center) Cat.-No AP51986PU-N, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Aff - Purified Hu, Por F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Beta-glucuronidase (C-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue reacted with Beta-glucuronidase Antibody (C-term) Cat.-No Cat.-No AP51987PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Beta-glucuronidase antibody

Beta-glucuronidase Mouse IgM 1A6 Ig Fraction E
1 mg / €410.00
  Acris Antibodies GmbH

Beta-glucuronidase antibody

Beta-glucuronidase Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Beta-glucuronidase antibody

Human Lung; GUSB antibody - C-terminal region (ARP44234_T100) in Human Lung cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Por, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

Beta-glucuronidase antibody

Beta-glucuronidase Rabbit IgG Aff - Purified Hu WB
0.1 mg / €290.00
  Boster Immunoleader

Beta-glucuronidase antibody

Beta-glucuronidase Mouse IgM 1A6 Hu E
0.5 mg / €360.00
  Novus Biologicals Inc.

Beta-glucuronidase antibody

Beta-glucuronidase Mouse IgG1 105 Hu, Rt C, E, WB
1 ml / €510.00
  Novus Biologicals Inc.

Beta-glucuronidase antibody

Western Blot: beta Glucuronidase Antibody [NBP1-69355] - This Anti-GUSB antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 2.5ug/ml. Rabbit Purified Hu P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Beta-glucuronidase antibody

Immunohistochemistry-Paraffin: beta Glucuronidase Antibody [NBP1-87511] - Immunohistochemical staining of human liver shows cytoplasmic positivity in bile duct cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Beta-glucuronidase

Beta-glucuronidase Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Beta-glucuronidase

Beta-glucuronidase Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Beta-glucuronidase

Beta-glucuronidase Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

GUSB 293T Cell Transient Overexpression Lysate(Denatured)

GUSB 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

GUSB overexpression lysate

GUSB overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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