Beta-hexosaminidase beta / HEXB antibody

Principal name

Beta-hexosaminidase beta / HEXB antibody

Alternative names for Beta-hexosaminidase beta / HEXB antibody

HCC7, N-acetyl-beta-glucosaminidase subunit beta, Beta-N-acetylhexosaminidase subunit beta, Cervical cancer proto-oncogene 7 protein

SwissProt ID

P07686 (Human), P20060 (Mouse), P49614 (Felca), Q29548 (Pig), Q6AXR4 (Rat)

Gene ID

3074 (HEXB)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Beta-hexosaminidase beta / HEXB antibody

Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Korneluk R.G., J. Biol. Chem. 261:8407-8413(1986).
Neote K., Genomics 3:279-286(1988).
Proia R.L., Proc. Natl. Acad. Sci. U.S.A. 85:1883-1887(1988).

14 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Beta-hexosaminidase beta / HEXB antibody

Western blot analysis of extracts from Jurkat cells, using HEXB antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Beta-hexosaminidase beta / HEXB (C-term) antibody

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Beta-hexosaminidase beta / HEXB antibody

Western Blot analysis of HEXB expression in transfected 293T cell line (H00003074-T01) by HEXB MaxPab polyclonal antibody.

Lane 1: HEXB transfected lysate(61.16 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Beta-hexosaminidase beta / HEXB antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using HEXB Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P, WB
50 µg / €205.00
  Assay Biotech

Beta-hexosaminidase beta / HEXB antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using HEXB Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P, WB
0.1 mg / €310.00
  Assay Biotech

Beta-hexosaminidase beta / HEXB antibody

Immunohistochemical analysis of HEXB staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Beta-hexosaminidase beta / HEXB antibody

Immunohistochemical analysis of HEXB staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Beta-hexosaminidase beta / HEXB antibody

Immunohistochemical analysis of HEXB staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Beta-hexosaminidase beta / HEXB antibody

Beta-hexosaminidase beta / HEXB Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Beta-hexosaminidase beta / HEXB antibody

Beta-hexosaminidase beta / HEXB Rabbit IgG Aff - Purified Hu E, P, WB
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Beta-hexosaminidase beta / HEXB

Beta-hexosaminidase beta / HEXB Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Beta-hexosaminidase beta / HEXB

Beta-hexosaminidase beta / HEXB Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Beta-hexosaminidase beta / HEXB

Beta-hexosaminidase beta / HEXB Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

HEXB 293T Cell Transient Overexpression Lysate(Denatured)

HEXB 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

14 Item(s)

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