BICD2 antibody

Principal name

BICD2 antibody

Alternative names for BICD2 antibody

Bic-D2, KIAA0699, Protein bicaudal D homolog 2

SwissProt ID

Q8TD16 (Human), Q921C5 (Mouse)

Gene ID

23299 (BICD2), 76895 (Bicd2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of BICD2 antibody

BICD2 is the second human homolog discovered to the Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. Similar to the highly homologous protein BICD1, BICD2 can bind to dynein-dynactin complex, primarily through the dynamitin subunit of dynactin. The C-terminus of BICD2 targets the protein to the Golgi complex while the N-terminal domain of BICD2 co-immunoprecipitates with cytoplasmic dynein, suggesting BICD2 plays a role in the dynein-dynactin interaction on the surface of membranous organelles. Mice engineered to overexpress the BICD2 amino terminal domain in neurons developed amyotrophic lateral sclerosis (ALS)-like features such as Golgi fragmentation, neurofilament swelling in proximal axons, etc., suggesting that impaired dynein/dynactin function may explain some of the pathological features observed in ALS patients.

9 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BICD2 (C-term) antibody

Western blot analysis of BICD2 in A549 cell lysate with BICD2 antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BICD2 (Center) antibody

Western blot analysis of BICD2 in A549 cell lysate with BICD2 antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BICD2 (C-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with BICD2 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BICD2 Control Peptide

BICD2
50 µg / €160.00
  Acris Antibodies GmbH

BICD2 Control Peptide

BICD2
50 µg / €160.00
  Acris Antibodies GmbH

BICD2 antibody

Western blot analysis of BICD2 in A-549 cell lysate with BICD2 polyclonal antibody ( Cat # PAB13387 ) at ( A ) 1 and ( B ) 2 µg/ml. Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

BICD2 antibody

Western blot analysis of BICD2 in A-549 cell lysate with BICD2 polyclonal antibody ( Cat # PAB13388 ) at ( A ) 1 and ( B ) 2 µg/ml. Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BICD2 (mGFP-tagged) - Human bicaudal D homolog 2 (Drosophila) (BICD2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, BICD2 (mGFP-tagged) - Human bicaudal D homolog 2 (Drosophila) (BICD2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,770.00
  OriGene Technologies, Inc.

Lenti ORF particles, BICD2 (Myc-DDK tagged) - Human bicaudal D homolog 2 (Drosophila) (BICD2), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, BICD2 (Myc-DDK tagged) - Human bicaudal D homolog 2 (Drosophila) (BICD2), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €1,590.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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