BICD2 antibody

Principal name

BICD2 antibody

Alternative names for BICD2 antibody

Bic-D2, KIAA0699, Protein bicaudal D homolog 2

SwissProt ID

Q8TD16 (Human), Q921C5 (Mouse)

Gene ID

23299 (BICD2), 76895 (Bicd2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of BICD2 antibody

BICD2 is the second human homolog discovered to the Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. Similar to the highly homologous protein BICD1, BICD2 can bind to dynein-dynactin complex, primarily through the dynamitin subunit of dynactin. The C-terminus of BICD2 targets the protein to the Golgi complex while the N-terminal domain of BICD2 co-immunoprecipitates with cytoplasmic dynein, suggesting BICD2 plays a role in the dynein-dynactin interaction on the surface of membranous organelles. Mice engineered to overexpress the BICD2 amino terminal domain in neurons developed amyotrophic lateral sclerosis (ALS)-like features such as Golgi fragmentation, neurofilament swelling in proximal axons, etc., suggesting that impaired dynein/dynactin function may explain some of the pathological features observed in ALS patients.

14 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BICD2 (C-term) antibody

  Rabbit Polyclonal BICD2 Antibody  
Western blot analysis of BICD2 in A549 cell lysate with BICD2 antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BICD2 (Center) antibody

  Rabbit Polyclonal BICD2 Antibody  
Western blot analysis of BICD2 in A549 cell lysate with BICD2 antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BICD2 (C-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with BICD2 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Bicd2 - mouse gene knockout kit via CRISPR

Bicd2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BICD2 (mGFP-tagged)-Human bicaudal D homolog 2 (Drosophila) (BICD2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, BICD2 (mGFP-tagged)-Human bicaudal D homolog 2 (Drosophila) (BICD2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, BICD2 (mGFP-tagged) - Human bicaudal D homolog 2 (Drosophila) (BICD2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, BICD2 (mGFP-tagged) - Human bicaudal D homolog 2 (Drosophila) (BICD2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,770.00
  OriGene Technologies, Inc.

Lenti ORF particles, BICD2 (Myc-DDK-tagged)-Human bicaudal D homolog 2 (Drosophila) (BICD2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, BICD2 (Myc-DDK-tagged)-Human bicaudal D homolog 2 (Drosophila) (BICD2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, BICD2 (Myc-DDK tagged) - Human bicaudal D homolog 2 (Drosophila) (BICD2), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, BICD2 (Myc-DDK tagged) - Human bicaudal D homolog 2 (Drosophila) (BICD2), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €1,590.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Bicd2 (GFP-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Bicd2 (GFP-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,580.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bicd2 (GFP-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Bicd2 (GFP-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,550.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bicd2 (GFP-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, Bicd2 (GFP-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,450.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bicd2 (Myc-DDK-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Bicd2 (Myc-DDK-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,420.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bicd2 (Myc-DDK-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Bicd2 (Myc-DDK-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,390.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bicd2 (Myc-DDK-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, Bicd2 (Myc-DDK-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,300.00
  OriGene Technologies, Inc.

14 Item(s)

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