Biglycan antibody

Principal name

Biglycan antibody

Alternative names for Biglycan antibody

Bone/cartilage proteoglycan I, PG-S1, PGS1, BGN, SLRR1A, Small Leucine-rich Protein 1A

SwissProt ID

O02678 (Canfa), P21809 (Bovin), P21810 (Human), P28653 (Mouse), P47853 (Rat)

Gene ID

633 (BGN), 12111 (Bgn), 25181

Available reactivities

Hu (Human), Rt (Rat), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Rb (Rabbit), Ze (Zebrafish), African clawed frog

Available hosts

Sheep, Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of Biglycan antibody

Biglycan (BGN) is a small leucine-rich repeat proteoglycan (SLRP) which is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. It is an important structural component of articular cartilage and participates in the assembly of the chondrocyte extracellular matrix through formation of protein interactions with type VI collagen and large proteoglycan aggregates. In humans, Biglycan is encoded by the BGN gene. It is mapped to Xq28. Biglycan is believed to play a role in the mineralisation of bone, and its core protein binds to the growth factors BMP-4 and influences its bioactivity. It has been reported that the presence of biglycan is necessary for BMP-4 to exert its effects on osteoblasts. There is also evidence that biglycan can bind to TGF-beta 1. In addition, Biglycan plays an important role in cell signaling.

General readings

Babelova A. et al. (2009) J Biol Chem. 284:24035-24048.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Biglycan (C-term) antibody

  Goat Polyclonal Antibody against Biglycan Preproprotein  
TA302434 (0.1µg/ml) staining of Rat Skin lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt E, WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

Biglycan antibody

  Rabbit anti-BGN Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using BGN antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €335.00
  OriGene Technologies, Inc.

Biglycan antibody

  Rabbit Polyclonal Anti-BGN Antibody  
BGN antibody - middle region (ARP56333_P050) validated by WB using Equine Cartilage Explants at 1:1000. Rabbit IgG Purified Hu, Ms, Por WB
50 µg / €360.00
  OriGene Technologies, Inc.

Biglycan antibody

  Rabbit Polyclonal Anti-BGN Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Hela cells, Primary antibody: (BGN Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Biglycan antibody

  Rabbit Polyclonal Biglycan Antibody  
ELISA: Biglycan Antibody Rabbit IgG Purified Hu E
50 µg / €409.00
  OriGene Technologies, Inc.

Biglycan (Center) antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with BGN Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Hu P, WB
0.4 ml / €370.00
  OriGene Technologies GmbH

Biglycan (N-term) antibody

Biglycan Sheep Purified Hu E
1 ml / €470.00
  OriGene Technologies GmbH

CRISPR

Catalog No. Species Donor Vector  

BGN - human gene knockout kit via CRISPR

BGN - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

BGN - human gene knockout kit via CRISPR

BGN - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

BGN - human gene knockout kit via CRISPR

BGN - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

BGN - human gene knockout kit via CRISPR

BGN - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Biglycan

  Recombinant protein of human biglycan (BGN)  
Biglycan Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €399.00
  OriGene Technologies, Inc.

Biglycan (38-368, His-tag)

Biglycan Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  OriGene Technologies GmbH

Biglycan (38-368, His-tag)

Biglycan Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  OriGene Technologies GmbH

ELISA Kits

Catalog No.    

Human Biglycan ELISA Kit

Human Biglycan ELISA Kit  
1 kit / €471.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

BGN overexpression lysate

BGN overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BGN (mGFP-tagged) - Human biglycan (BGN), 200 uL, >10^7 TU/mL

Lenti ORF particles, BGN (mGFP-tagged) - Human biglycan (BGN), 200 uL, >10^7 TU/mL  
200 µl / €1,082.00
  OriGene Technologies, Inc.

Lenti ORF particles, BGN (Myc-DDK tagged) - Human biglycan (BGN) , 200 uL, >10^7 TU/mL

Lenti ORF particles, BGN (Myc-DDK tagged) - Human biglycan (BGN) , 200 uL, >10^7 TU/mL  
200 µl / €969.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Bgn (GFP-tagged) - Mouse biglycan (Bgn), 200 uL, >10^7 TU/mL

Lenti ORF particles, Bgn (GFP-tagged) - Mouse biglycan (Bgn), 200 uL, >10^7 TU/mL  
200 µl / €907.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bgn (Myc-DDK-tagged) - Mouse biglycan (Bgn), 200 uL, >10^7 TU/mL

Lenti ORF particles, Bgn (Myc-DDK-tagged) - Mouse biglycan (Bgn), 200 uL, >10^7 TU/mL  
200 µl / €804.00
  OriGene Technologies, Inc.

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