BIK antibody

Principal name

BIK antibody

Alternative names for BIK antibody

Bcl-2-interacting killer, NBK, BP4, BIP1, Apoptosis inducer NBK

SwissProt ID

Q13323 (Human)

Gene ID

638 (BIK)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Immunoprecipitation (IP)

Background of BIK antibody

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by the activation of proteolytic enzymes termed caspases. Proteins that comprise the Bcl-2 family appear to control the activation of these enzymes. One such protein BIK was recently identified as an endoplasmic reticulum (ER)-residing pro-apoptotic member of the Bcl-2 homology domain-3 (BH3)-only group of the Bcl-2 family that stimulates mitochondrial release of cytochrome c following p53 induction of apoptosis. A significant fraction of BIK is found as an ER transmembrane protein, with most of the protein facing the cytosol. Restricting BIK to the ER membrane by replacing the transmembrane region with that of the ER-selective membrane anchor of cytochrome b resulted in a decreased cytochrome c release from mitochondria and a corresponding drop in cell death. Recent evidence suggests that BIK cooperates with NOXA, another BH3-only protein, to somehow enhance the activation of Bax to stimulate the rapid release of cytochrome c from mitochondria.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BIK antibody

Western blot analysis of BIK in Jurkat cell lysate with BIK antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BIK antibody

Western blot analysis of extracts from HeLa cells, using BIK (Ab-35) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BIK antibody

Western blot analysis of extracts from A549 cells, treated with DMSO (0.1%, 10mins), using BIK (Ab-33) antibody (#TA313507, Line 1 and 2).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BIK antibody

Western blot analysis of BIK expression in A549 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BIK antibody

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG 4G12 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

BIK (N-term) antibody

Immunocytochemical staining of Jurkat cells with Rabbit anti Human BIK (AP05587PU-N) Rabbit IgG Purified Hu, Ms ICC/IF, WB
0.1 mg / €330.00
  Acris Antibodies GmbH

BIK antibody

Immunohistochemical analysis in paraffin-embedded human lung carcinoma tissue using BIK  antibody (Cat.-No. AP06031PU-N). Rabbit Aff - Purified Hu E, ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

BIK antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Prostate. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

BIK (BH3 Domain) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BIK pThr33 antibody

AP12573PU-N BIK antibody staining of Formalin-Fixed and Paraffin-Embedded Human cancer tissue. The primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB

Regular Price: 0.4 ml / €370.00

Special Price: 0.4 ml / €231.00

  Acris Antibodies GmbH

BIK Control Peptide

BIK
50 µg / €160.00
  Acris Antibodies GmbH

BIK antibody

Immunoperoxidase of monoclonal antibody to BIK on formalin-fixed paraffin-embedded human lung. [antibody concentration 3 ug/ml] Mouse IgG 4G12 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

BIK antibody

Formalin-fixed, paraffin-embedded tissue section of human kidney stained for BIK expression. Using BIK polyclonal antibody ( Cat # PAB0239 ) at 1 : 2000. A high level of BIK signal was seen in the distal collecting tubules, the glomeruli are primarily negative. Hematoxylin-eosin counterstain. Rabbit Hu, Ms, Rt C, IP, P
50 µl / €390.00
  Abnova Taiwan Corp.

BIK antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the BIK polyclonal antibody ( Cat # PAB2449 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

BIK antibody

Immunocytochemistry of BIK in Jurkat cells with BIK polyclonal antibody ( Cat # PAB12962 ) at 1 µg/ml. Rabbit Hu, Ms ICC/IF, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

BIK pThr33 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using BIK (Phospho-Thr33) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P, WB
50 µg / €205.00
  Assay Biotech

BIK pThr33 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using BIK (Phospho-Thr33) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P, WB
0.1 mg / €310.00
  Assay Biotech

BIK antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using BIK (Ab-33) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

BIK antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using BIK (Ab-33) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

BIK pThr33 antibody

Immunohistochemical analysis of BIK (pT33) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu IP, P, WB
30 µl / €210.00
  Cohesion Biosciences Ltd.

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