Bile salt export pump / BSEP antibody

Principal name

Bile salt export pump / BSEP antibody

Alternative names for Bile salt export pump / BSEP antibody

ABCB11, SPGP, Sister of P-glycoprotein, ATP-binding cassette sub-family B member 11

SwissProt ID

O70127 (Rat), O95342 (Human), Q9N0V3 (Rabit), Q9QY30 (Mouse)

Gene ID

8647 (ABCB11), 27413 (Abcb11)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Bile salt export pump / BSEP antibody

ABCB11 is involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes. It is expressed predominatly, if not exclusively, in the liver, where it is further localized to the canilicular microvilli and to subcanilicular vesicles fo the hepatocytes. Structurally, ABCB11 is a multifunctional polypeptide with two homologus halves, each containing a hydrophobic membrane-anchoring domain and an ATP binding cassette (ABC) domain. Defects in ABCB11 are the cause of progressive familial intrahepatic cholestasis 2 (PFIC2). PFIC2 is an inherited liver disease of childhood which is characterized by cholestasis and normal serum gamma-glutamyltransferase activity. Defects in ABCB11 are also found in cases of chronic intrahepatic cholestasis without obvious familial history of chronic liver disease.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Bile salt export pump / BSEP antibody

Predicted cell location: Cytoplasm . Positive control: Human ovarian and liver cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using ABCB11 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Bile salt export pump / BSEP antibody

Predicted cell location: Cytoplasm . Positive control: Human ovarian and lung cancer tissue . Recommended dilution: 1/15-50  The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using ABCB11 antibody at dilution 1/15, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Bile salt export pump / BSEP (C-term) antibody

Immunohistochemistry: AP13073PU-N ABCB11 antibody staining of Formalin-Fixed Paraffin-Embedded Human cancer followed by peroxidase-conjugation to the secondary antibody and AEC staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Bile salt export pump / BSEP antibody

Bile salt export pump / BSEP Mouse IgG1 USal-hBSEP-McAb-1 Hu ICC/IF, WB
0.1 mg / €640.00
  Abnova Taiwan Corp.

Bile salt export pump / BSEP antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with ABCB11 polyclonal antibody ( Cat # PAB4697 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

Bile salt export pump / BSEP antibody

Bile salt export pump / BSEP Rabbit Hu, Ms, Rt WB
0.2 ml / €560.00
  Abnova Taiwan Corp.

Bile salt export pump / BSEP antibody

Bile salt export pump / BSEP Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Bile salt export pump / BSEP antibody

Bile salt export pump / BSEP Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

Bile salt export pump / BSEP antibody

Western Blot: ABCB11 Antibody [NBP1-31824] - (30 ug of whole cell lysate)  A: JurKat  5% SDS PAGE  diluted at 1:1000 Rabbit IgG Hu ICC/IF, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Bile salt export pump / BSEP antibody

Immunohistochemistry-Paraffin: ABCB11 Antibody [NBP1-89319] Immunohistochemical staining of human liver shows moderate membranous positivity in hepatocytes. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

10 Item(s)

per page
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