BIRC6 antibody

Principal name

BIRC6 antibody

Alternative names for BIRC6 antibody

KIAA1289, Apollon, Baculoviral IAP repeat-containing protein 6, Ubiquitin-conjugating BIR domain enzyme apollon

SwissProt ID

Q9NR09 (Human)

Gene ID

57448 (BIRC6)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP), PLA/Proximity ligation assay (PLA), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of BIRC6 antibody

BRUCE Antibody: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. BRUCE, also known as BIRC6, is an IAP family member protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. BRUCE regulates p53 and the mitochondrial pathway of apoptosis by facilitating the degradation of apoptotic proteins such as Caspase-9 and SMAC by ubiquitition.

General readings

Chen Z, Naito M, Hori S, et al. A human IAP-gamily gene, apollon, expressed in human brain cancer cells. Biochem. Biophys. Res. Commun. 1999; 264:847-54.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BIRC6 (C-term) antibody

Immunohistochemistry of BRUCE in human small intestine tissue with BRUCE antibody at 5 ug/mL. Rabbit IgG Aff - Purified Hu E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

BIRC6 antibody

Predicted cell location: Cytoplasm. Positive control: Human cervical cancer tissue. Recommended dilution: 1/10-50  The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using BIRC6 antibody at dilution 1/7, on the right is treated with the synthetic peptide. (Original magnification: x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

BIRC6 antibody

Predicted cell location: Cytoplasm, Cell membrane. Positive control: Human tonsil and liver cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using BIRC6 antibody at dilution 1/50, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

BIRC6 antibody

Predicted cell location: Cytoplasm . Positive control: Human colon and ovarian cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using BIRC6 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

BIRC6 antibody

Predicted cell location: Cytoplasm . Positive control: Human brain and gastric cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human brain tissue using BIRC6 antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

BIRC6 (C-term) Control Peptide

BIRC6
50 µg / €160.00
  Acris Antibodies GmbH

BIRC6 antibody

BIRC6 Mouse Serum Hu E
50 µl / €290.00
  Abnova Taiwan Corp.

BIRC6 antibody

BIRC6 Goat Hu E
0.1 mg / €390.00
  Abnova Taiwan Corp.

BIRC6 antibody

Immunohistochemistry-Paraffin: BIRC6 Antibody [NB300-264] - FFPE section of human ovarian tumor.  Affinity purified rabbit anti-BIRC6/Apollon used at a dilution of 1:250.  Detection: DAB staining using Immunohistochemistry Accessory Kit Rabbit Aff - Purified Hu ICC/IF, IP, P, PLA, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

BIRC6

BIRC6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

BIRC6

BIRC6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

11 Item(s)

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