BIRC7 / LIVIN antibody

Principal name

BIRC7 / LIVIN antibody

Alternative names for BIRC7 / LIVIN antibody

KIAP, MLIAP, RNF50, Baculoviral IAP repeat-containing protein 7, Kidney inhibitor of apoptosis protein, Melanoma inhibitor of apoptosis protein, Livin, RING finger protein 50

SwissProt ID

Q96CA5 (Human)

Gene ID

79444 (BIRC7)

Available reactivities

Hu (Human), Bov (Bovine), Mky (Monkey), Prim (Primate), Bear, Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Enzyme Immunoassay (E), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of BIRC7 / LIVIN antibody

BIRC7 protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis.The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.

General readings

Puri N et al. Telomere-based DNA damage responses: a new approach to melanoma. FASEB J. 2004 Sep;18(12):1373-81.
PMID: 15333580

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BIRC7 / LIVIN antibody

  anti-BIRC7 (Livin) mouse monoclonal antibody, clone OTI1D12 (formerly 1D12)  
Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-BIRC7mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500758, Dilution 1:50) Mouse IgG1 OTI1D12 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

BIRC7 / LIVIN antibody

  anti-BIRC7 (Livin) mouse monoclonal antibody, clone OTI1B10 (formerly 1B10)  
Anti-BIRC7 mouse monoclonal antibody (TA500761) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BIRC7(RC204906). Mouse IgG1 OTI1B10 Purified Hu F, ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

BIRC7 / LIVIN (C-term) antibody

  Goat Polyclonal Antibody against LIVIN / BIRC7  
TA302674 staining (0.3µg/ml) of MOLT4 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BIRC7 / LIVIN antibody

  Rabbit Polyclonal Livin Antibody  
Western blot analysis of Livin expression in human Raji cell lysate with Livin antibody at 0.5 ug/ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BIRC7 / LIVIN antibody

  Rabbit polyclonal antibody to ML-IAP (baculoviral IAP repeat-containing 7)  
Livin antibody detects BIRC7 protein by Western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug A431 whole cell lysate/extract. C. 30 ug HepG2 whole cell lysate/extract. 12 % SDS-PAGE. Livin antibody (TA308543) dilution: 1:500 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BIRC7 / LIVIN antibody

  Rabbit Polyclonal antibody to Livin (baculoviral IAP repeat-containing 7)  
Immunohistochemical analysis of paraffin-embedded SAS xenograft , using ML-IAP(TA308807) antibody at 1:100 dilution. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

BIRC7 / LIVIN antibody

  Anti-BIRC7 Rabbit Polyclonal Antibody  
Western blot analysis of Human fetal brain tissue using TA322202(BIRC7 Antibody) at dilution 1/400 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BIRC7 / LIVIN antibody

  Anti-BIRC7 Rabbit Polyclonal Antibody  
Western blot analysis of A549, Jurkat, Raji and Hela cell using TA322203(BIRC7 Antibody) at dilution 1/600 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BIRC7 / LIVIN antibody

  Rabbit Polyclonal Anti-BIRC7 Antibody  
WB Suggested Anti-BIRC7 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

BIRC7 / LIVIN antibody

  Rabbit anti-BIRC7 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using BIRC7 antibody. Rabbit IgG Purified Hu, Ms
0.1 mg / €325.00
  OriGene Technologies, Inc.

BIRC7 / LIVIN antibody

  Mouse Monoclonal Livin Antibody (88C570)  
Western Blot: Livin Antibody (88C570) [TA336400] - detection of Livin in A) Livin transfected cell lysate and B) Molt4 cell lysate. A protein band of apprximate molecular weight of 31 kDa is detected using this antibody. Mouse IgG1 88C570 Purified Hu ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BIRC7 / LIVIN antibody

Formalin-Fixed Paraffin-Embedded Human Heart stained with BIRC7 / Livin Antibody Cat.-No AM08363PU-N at 10 µg/ml after heat-induced antigen retrieval. Mouse IgG1 88C570 Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

BIRC7 / LIVIN antibody

BIRC7 / LIVIN Rabbit Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

BIRC7 / LIVIN (264-298) antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Brain, cerebellum. Rabbit Aff - Purified Hu, Mky P, WB
50 µg / €470.00
  Acris Antibodies GmbH

BIRC7 / LIVIN (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BIRC7 / LIVIN antibody

Western blot analysis of ML-IAP antibody (Cat.-No.: AP20649PU-N) in extracts from COLO cells. Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

BIRC7 / LIVIN antibody

Western blot analysis of Livin (BIRC7) in Jurkat cell lysate with SP1358P. Goat Purified Hu WB
0.1 mg / €550.00
  Acris Antibodies GmbH

BIRC7 / LIVIN antibody

Detection of Livin α and β. 0.5 ng of His tagged recombinant human Livin-α and human Livin-β , and lysates from 0.5 x 106 human SK-Mel-28 cells were resolved by SDS-PAGE, transferred to Immobilon membrane and immunoblotted with 0.5 μg/mL goat anti-Livin. A 60 second exposure to film is shown. Goat IgG Aff - Purified Hu WB
0.1 mg / €450.00
  Neuromics Antibodies

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

BIRC7 / LIVIN (transcript variant 1)

  Recombinant protein of human baculoviral IAP repeat-containing 7 (BIRC7), transcript variant 1  
BIRC7 / LIVIN Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

BIRC7 / LIVIN (transcript variant 2)

  Recombinant protein of human baculoviral IAP repeat-containing 7 (BIRC7), transcript variant 2  
BIRC7 / LIVIN Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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