BIRC8 / ILP2 antibody

Principal name

BIRC8 / ILP2 antibody

Alternative names for BIRC8 / ILP2 antibody

ILP-2, IAP-like protein 2, Baculoviral IAP repeat-containing protein 8, Inhibitor of apoptosis-like protein 2, Testis-specific inhibitor of apoptosis

SwissProt ID

Q96P09 (Human)

Gene ID

112401 (BIRC8)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of BIRC8 / ILP2 antibody

Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2 (1). ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues (1). ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BIRC8 / ILP2 antibody

  Rabbit Polyclonal ILP-2 Antibody  
Western blot analysis of ILP-2 expression in human HepG2 (lane 1) and MOLT4 (lane 2) cell lysates with ILP-2 antibody at 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BIRC8 / ILP2 antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Small intestine, Peyer's patch. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

BIRC8 / ILP2 (2-13) antibody

Immunocytochemical staining of HepG2 cells with Rabbit anti ILP-2 (SP1413P) Rabbit Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

BIRC8 - human gene knockout kit via CRISPR

BIRC8 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

BIRC8 - human gene knockout kit via CRISPR

BIRC8 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

BIRC8 - human gene knockout kit via CRISPR

BIRC8 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

BIRC8 - human gene knockout kit via CRISPR

BIRC8 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BIRC8 (mGFP-tagged) - Human baculoviral IAP repeat containing 8 (BIRC8), 200 uL, >10^7 TU/mL

Lenti ORF particles, BIRC8 (mGFP-tagged) - Human baculoviral IAP repeat containing 8 (BIRC8), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, BIRC8 (Myc-DDK tagged) - Human baculoviral IAP repeat containing 8 (BIRC8) , 200 uL, >10^7 TU/mL

Lenti ORF particles, BIRC8 (Myc-DDK tagged) - Human baculoviral IAP repeat containing 8 (BIRC8) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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