BIRC8 / ILP2 antibody
Principal name
BIRC8 / ILP2 antibody
Alternative names for BIRC8 / ILP2 antibody
ILP-2, IAP-like protein 2, Baculoviral IAP repeat-containing protein 8, Inhibitor of apoptosis-like protein 2, Testis-specific inhibitor of apoptosis
SwissProt ID
Q96P09 (Human)
Gene ID
112401 (BIRC8)
Ncbi ID
Available reactivities
Available hosts
Available applications
Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Enzyme Immunoassay (E)
Background of BIRC8 / ILP2 antibody
Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2 (1). ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues (1). ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA306099 | BIRC8 / ILP2 antibody |
||||||
| Rabbit Polyclonal ILP-2 Antibody | |||||||
 |
Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, ICC/IF, WB |
0.1 mg /
€325.00
|
|
| OriGene Technologies, Inc. | |||||||
 +2 additional images |
|||||||
| AP07671PU-N | BIRC8 / ILP2 antibody |
||||||
 |
Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
50 µg /
€470.00
|
||
| Acris Antibodies GmbH | |||||||
| SP1413P | BIRC8 / ILP2 (2-13) antibody |
||||||
 |
Rabbit | Purified | Hu, Ms, Rt | ICC/IF, WB |
0.1 mg /
€320.00
|
||
| Acris Antibodies GmbH | |||||||
| +1 additional image |
|||||||
CRISPR
| Catalog No. | Species | Donor Vector | |
|---|---|---|---|
| KN207245 | BIRC8 - human gene knockout kit via CRISPR |
||
 |
Human | GFP-Puro |
1 kit /
€1,200.00
|
| OriGene Technologies, Inc. | |||
| KN207245BN | BIRC8 - human gene knockout kit via CRISPR |
||
|
Human | mBFP-Neo |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN207245LP | BIRC8 - human gene knockout kit via CRISPR |
||
|
Human | Luciferase-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN207245RB | BIRC8 - human gene knockout kit via CRISPR |
||
|
Human | RFP-BSD |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC207245L2V | Lenti ORF particles, BIRC8 (mGFP-tagged) - Human baculoviral IAP repeat containing 8 (BIRC8), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€880.00
|
|
| OriGene Technologies, Inc. | ||
| RC207245L1V | Lenti ORF particles, BIRC8 (Myc-DDK tagged) - Human baculoviral IAP repeat containing 8 (BIRC8) , 200 uL, >10^7 TU/mL |
|
|
200 µl /
€780.00
|
|
| OriGene Technologies, Inc. | ||
