Blood Group Lewis a Antigen antibody

Principal name

Blood Group Lewis a Antigen antibody

Available reactivities

Hu (Human)

Available hosts

Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Blood Group Lewis a Antigen antibody

Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

General readings

This product has been used in:Creuzot-Garcher C et al. Alteration of sialyl Lewis epitope expression in pterygium. Invest Ophthalmol Vis Sci 40:1631-6 (1999). PubMed PMID: 10393028
Torrado J et al. Lewis antigen alterations in gastric cancer precursors. Gastroenterology 102:424-30 (1992). PubMed PMID: 1732113
Bara J et al. Immunochemical characterization of mucins. Polypeptide (M1) and polysaccharide (A and Leb) antigens. Biochem J 254:185-93 (1988). PubMed PMID: 2460087
First International Workshop on Monoclonal Antibodies Against Red Blood Cell and Related Antigens. Vol II: Other blood group systems. (1987).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Blood Group Lewis a Antigen antibody

Immunohistochemistry staining of colorectal adenocarcinoma (paraffin-embedded sections) with anti-human Blood Group Lewis a (7LE). Mouse IgG1 7LE Purified Hu E, P, WB
0.1 mg / €190.00
  Acris Antibodies GmbH

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