Blood Group Lewis b Antigen antibody

Principal name

Blood Group Lewis b Antigen antibody

Alternative names for Blood Group Lewis b Antigen antibody

Blood Group Antigen Lewis b

Available reactivities

Hu (Human)

Available hosts


Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Blood Group Lewis b Antigen antibody

Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

General readings

This product has been used in:Creuzot-Garcher C et al. Alteration of sialyl Lewis epitope expression in pterygium. Invest Ophthalmol Vis Sci 40:1631-6 (1999). PubMed PMID: 10393028
Torrado J et al. Lewis antigen alterations in gastric cancer precursors. Gastroenterology 102:424-30 (1992). PubMed PMID: 1732113
Bara J et al. Immunochemical characterization of mucins. Polypeptide (M1) and polysaccharide (A and Leb) antigens. Biochem J 254:185-93 (1988). PubMed PMID: 2460087
First International Workshop on Monoclonal Antibodies Against Red Blood Cell and Related Antigens. Vol. II: Other blood group systems. (1987).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Blood Group Lewis b Antigen antibody

Formalin-fixed, paraffin-embedded human colon stained with Lewis B Antibody (Cat#SM3092) using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of epithelial cells. Mouse IgG1 2-25LE Purified Hu E, P, WB
0.1 mg / €190.00
  Acris Antibodies GmbH

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