BMP13 / GDF6 antibody

Principal name

BMP13 / GDF6 antibody

Alternative names for BMP13 / GDF6 antibody

Bone Morphogenetic Protein 13, GDF-6, GDF16, GDF-16, CDMP2, Cartilage Derived Morphogenetic Protein 2

SwissProt ID

P43028 (Mouse), P55106 (Bovin), Q6HA10 (Rat), Q6KF10 (Human)

Gene ID

392255 (GDF6)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Flow Cytometry (F), Paraffin Sections (P), Frozen Sections (C)

Background of BMP13 / GDF6 antibody

Bone Morphogenetic Proteins (BMPs) are members of the TGF beta superfamily of cytokines that affect bone and cartilage formation. Similar to other TGF beta family proteins, BMPs are highly conserved across animal species. Mature BMPs are 30-38 kDa proteins that assume a TGF beta like cysteine knot configuration. Unlike TGF beta, BMPs do not form latent complexes with their propeptide counterparts. Most BMPs are homodimers, but bioactive natural heterodimers have been reported. Recently it was found that lovostatin, widely used for lowering cholesterol, also increases bone formation by turning on a gene (bmp2) that promotes local bone formation. BMPs create an environment conducive for bone marrow development by stimulating the production of specific bone matrix proteins and altering stromal cell and osteoclast proliferation. In addition to stimulating ectopic bone and cartilage development, BMPs may be an important factor in the development of the viscera, with roles in cell proliferation, apoptosis, differentiation, and morphogenesis. BMPs also appear to be responsible for normal dorsal/ventral patterning. BMPs are found in tissues that induce bone or cartilage growth, such as demineralized bone and urinary epithelium. Cellular responses to BMP5 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors which play significant roles in BMP binding and signaling. One BMP type II receptor and two BMP type I receptors have been identified.

General readings

Gonzalez-Rodriguez, J., et al. Br J Ophthalmol 94(8):1100-1104(2010)
Mikic, B., et al. J. Orthop. Res. 27(12):1603-1611(2009)
Asai-Coakwell, M., et al. Hum. Mol. Genet. 18(6):1110-1121(2009)
Zhang, X., et al. Mol. Vis. 15, 2911-2918 (2009)
Shen, B., et al. Int. J. Biol. Sci. 5(2):192-200(2009)

14 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BMP13 / GDF6 (C-term) antibody

Western blot analysis of GDF6 in SK-N-SH lysate with GDF6 antibody at (A) 0.5 and (B) 1 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BMP13 / GDF6 antibody

Predicted band size: 51 kDa . Positive control: Human fetal liver and bladder carcinoma tissue lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lane1: Human fetal liver tissue lysate Lane2: Human bladder carcinoma tissue lysate Lysates: 40 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BMP13 / GDF6 antibody

Predicted band size: 51 kDa . Positive control: Human fetal muscle tissue lysate. Recommended dilution: 1/200-1000. (Gel: 8%SDS-PAGE Lysate: 40 ug Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BMP13 / GDF6 Control Peptide

BMP13 / GDF6
50 µg / €160.00
  Acris Antibodies GmbH

BMP13 / GDF6 (N-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue reacted with BMP13 / GDF6 Antibody (N-term) Cat.-No AP51812PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Purified Hu, Ms F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BMP13 / GDF6 antibody

Western blot analysis of GDF6 using recombinant human GDF6. Rabbit Hu WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

BMP13 / GDF6 antibody

Western blot analysis of GDF6 in SK-N-SH lysate with GDF6 polyclonal antibody ( Cat # PAB13050 ) at ( A ) 0.5 and ( B ) 1 µg/ml. Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

BMP13 / GDF6 antibody

Western Blot: GDF6 Antibody [NBP1-45406] - Western blot analysis using
recombinant human BMP-13
(Cat.# 4639-10). Both monome
and dimer can be detected. Rabbit IgG Aff - Purified Hu WB
0.1 mg / €440.00
  Novus Biologicals Inc.

BMP13 / GDF6 antibody

Western Blot: GDF6 Antibody [NBP1-76364] - Analysis of GDF6 in SK-N-SH lysate with GDF6 antibody at (A) 0.5 and (B) 1 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

BMP13 / GDF6 antibody

Immunohistochemistry-Paraffin: GDF6 Antibody [NBP1-91934] - Immunohistochemical staining of human stomach, lower shows strong membranous and cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

BMP13 / GDF6

BMP13 / GDF6 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 50 µg / €199.00

Special Price: 50 µg / €139.00

  OriGene Technologies, Inc.

BMP13 / GDF6

BMP13 / GDF6 Human Purified > 95 % by SDS-PAGE and HPLC analyses E. coli
10 µg / €140.00
  Acris Antibodies GmbH

BMP13 / GDF6

BMP13 / GDF6 Human Purified > 95 % by SDS-PAGE and HPLC analyses E. coli
50 µg / €230.00
  Acris Antibodies GmbH

BMP13 / GDF6

BMP13 / GDF6 Human
10 µg / €290.00
  Abnova Taiwan Corp.

14 Item(s)

per page
  • LinkedIn