BMP5 antibody

Principal name

BMP5 antibody

Alternative names for BMP5 antibody

Bone morphogenetic protein 5, BMP-5

SwissProt ID

P22003 (Human), P49003 (Mouse)

Gene ID

653 (BMP5)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Chk (Chicken), Por (Porcine), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Goat, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection))

Background of BMP5 antibody

Bone Morphogenetic Proteins (BMPs) are members of the TGF beta superfamily of cytokines that affect bone and cartilage formation. Similar to other TGF beta family proteins, BMPs are highly conserved across animal species. Mature BMPs are 30-38 kDa proteins that assume a TGF beta like cysteine knot configuration. Unlike TGF beta, BMPs do not form latent complexes with their propeptide counterparts. Most BMPs are homodimers, but bioactive natural heterodimers have been reported. Recently it was found that lovostatin, widely used for lowering cholesterol, also increases bone formation by turning on a gene (bmp2) that promotes local bone formation. BMPs create an environment conducive for bone marrow development by stimulating the production of specific bone matrix proteins and altering stromal cell and osteoclast proliferation. In addition to stimulating ectopic bone and cartilage development, BMPs may be an important factor in the development of the viscera, with roles in cell proliferation, apoptosis, differentiation, and morphogenesis. BMPs also appear to be responsible for normal dorsal/ventral patterning. BMPs are found in tissues that induce bone or cartilage growth, such as demineralized bone and urinary epithelium. Cellular responses to BMP5 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors which play significant roles in BMP binding and signaling. One BMP type II receptor and two BMP type I receptors have been identified.
BMP5 induces cartilage and bone formation and is expressed in lung and liver tissue.

General readings

Mailhot G., et al. (2008). J Cell Physiol. 214(1):56-64.
Matus DQ., et al. (2006). Proc Natl Acad Sci U S A. 103(30):11195-200.

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BMP5 (31-46) antibody

  BMP5 Rabbit Polyclonal (aa31-46) Antibody  
Anti-BMP5 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. Rabbit Purified Hu E, P
50 µg / €400.00
  OriGene Technologies, Inc.

BMP5 antibody

  Rabbit polyclonal anti-BMP-5 antibody  
Western blot analysis using recombinant human BMP-5. Lane 1: 50 ng, Lane2: 100 ng, Lane 3: 200 ng, Lane 4: 500 ng. Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BMP5 antibody

  Rabbit polyclonal anti-BMP-5 antibody  
Western blot analysis of BMP-5 expression using 3T3 cell lysate. Rabbit Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BMP5 antibody

  Rabbit Polyclonal Anti-BMP5 Antibody  
Host: Rabbit; Target Name: Bmp5; Sample Tissue: Rat Brain lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

BMP5 (N-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BMP5 antibody

Immunohistochemistry analysis of BMP-5 Antibody (Cat.-No AP20581PU-N) in paraffin-embedded human heart tissue. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

BMP5 antibody

BMP5 Goat Aff - Purified Hu, Rt C, E, ICC/IF, WB
0.1 mg / €450.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

BMP5 - human gene knockout kit via CRISPR

BMP5 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

BMP5 - human gene knockout kit via CRISPR

BMP5 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

BMP5 - human gene knockout kit via CRISPR

BMP5 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

BMP5 - human gene knockout kit via CRISPR

BMP5 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

BMP5

  Purified recombinant protein of Human bone morphogenetic protein 5 (BMP5).  
BMP5 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
CHO cells

Regular Price: 10 µg / €399.00

Special Price: 10 µg / €239.00

  OriGene Technologies, Inc.

BMP5 (317-454)

BMP5 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €990.00
  Acris Antibodies GmbH

BMP5 (317-454)

BMP5 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BMP5 (mGFP-tagged) - Human bone morphogenetic protein 5 (BMP5), 200 uL, >10^7 TU/mL

Lenti ORF particles, BMP5 (mGFP-tagged) - Human bone morphogenetic protein 5 (BMP5), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, BMP5 (Myc-DDK tagged) - Human bone morphogenetic protein 5 (BMP5) , 200 uL, >10^7 TU/mL

Lenti ORF particles, BMP5 (Myc-DDK tagged) - Human bone morphogenetic protein 5 (BMP5) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

16 Item(s)

per page
  • LinkedIn