BNIP3L / BNIP3A antibody

Principal name

BNIP3L / BNIP3A antibody

Alternative names for BNIP3L / BNIP3A antibody

BNIP3H, NIX, NIP3-like protein X, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A, Adenovirus E1B19K-binding protein B5, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

SwissProt ID

O60238 (Human), Q3T013 (Bovin), Q9Z2F7 (Mouse)

Gene ID

665 (BNIP3L), 12177 (Bnip3l)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Flow Cytometry (F), Frozen Sections (C)

Background of BNIP3L / BNIP3A antibody

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and desigted Bnip3L, Bnip3alpha, and Nix (for Nip3-like protein X) (1-3). Bnip3L/Bnip3alpha/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis (2,3). Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria. The messenger R of Bnip3L is ubiquitously expressed in human tissues (1,2). Bnip3L and Bnip3 form a new subfamily of the pro-apoptotic mitochondrial proteins.

General readings

Novak, I., et al. EMBO Rep. 11(1):45-51(2010)
Bellot, G., et al. Mol. Cell. Biol. 29(10):2570-2581(2009)
Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)
Papandreou, I., et al. Cell Death Differ. 15(10):1572-1581(2008)
Liu, W., et al. Neoplasia 10(8):897-907(2008)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BNIP3L / BNIP3A antibody

Western blot analysis using anti-Bnip3L (IN) antibody at 1 µg/ml on K562 whole cell lysate in the absense (1) and presense (2) of immunogenic peptide. Rabbit IgG Purified Hu WB
0.1 mg / €440.00
  Acris Antibodies GmbH

BNIP3L / BNIP3A (Center) antibody

Confocal immunofluorescent analysis of BNIP3L / BNIP3A Antibody (Center) Cat.-No AP52881PU-N with A549 cell followed by Alexa Fluor®488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue). Rabbit Ig Aff - Purified Hu F, ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BNIP3L / BNIP3A antibody

  Rabbit Polyclonal Bnip3L Antibody  
Western blot analysis of Bnip3L in K562 whole cell lysate in the absence (A), or presence (B) of immunogenic peptide (2289P) with Bnip3L antibody (IN) at 1 ug/ml. Rabbit IgG Purified Hu ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BNIP3L / BNIP3A antibody

  Rabbit Polyclonal BNIP3L Antibody  
Immunohistochemistry: BNIP3L Antibody [TA336844] - Analysis of BNIP3L in mouse prostate using DAB with hematoxylin counterstain. Rabbit Purified Hu, Ms C, ICC/IF, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

BNIP3L / BNIP3A antibody

  Rabbit Polyclonal anti-Bnip3L Antibody  
BNIP3L / BNIP3A Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

BNIP3L / BNIP3A antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Kidney. Rabbit Aff - Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Bnip3l - mouse gene knockout kit via CRISPR

Bnip3l - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BNIP3L (mGFP-tagged) - Human BCL2/adenovirus E1B 19kDa interacting protein 3-like (BNIP3L), 200 uL, >10^7 TU/mL

Lenti ORF particles, BNIP3L (mGFP-tagged) - Human BCL2/adenovirus E1B 19kDa interacting protein 3-like (BNIP3L), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, BNIP3L (Myc-DDK tagged) - Human BCL2/adenovirus E1B 19kDa interacting protein 3-like (BNIP3L) , 200 uL, >10^7 TU/mL

Lenti ORF particles, BNIP3L (Myc-DDK tagged) - Human BCL2/adenovirus E1B 19kDa interacting protein 3-like (BNIP3L) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Bnip3l (GFP-tagged) - Mouse BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), 200 uL, >10^7 TU/mL

Lenti ORF particles, Bnip3l (GFP-tagged) - Mouse BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bnip3l (Myc-DDK-tagged) - Mouse BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), 200 uL, >10^7 TU/mL

Lenti ORF particles, Bnip3l (Myc-DDK-tagged) - Mouse BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

11 Item(s)

per page
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