BOK / BCL2L9 antibody

Principal name

BOK / BCL2L9 antibody

Alternative names for BOK / BCL2L9 antibody

Bcl-2-like protein 9, Hbok, Bcl2-L-9, Bcl-2-related ovarian killer protein

SwissProt ID

O35425 (Mouse), Q792S6 (Rat), Q9I8I2 (Chick), Q9UMX3 (Human)

Gene ID

29884 (Bok), 666 (BOK)

Available reactivities

Rt (Rat), Ms (Mouse), Hu (Human)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of BOK / BCL2L9 antibody

Apoptosis or programmed cell death is a physiological cellular process characterized by cell shrinkage, membrane blebbing, DNA fragmentation, and release of Cytochrome C from the mitochondria. It is utilized by the organism to get rid of unwanted cells, which is critical for normal development and homeostasis of an organism. Disregulation of normal apoptosis process have been implicated in a variety of diseases, including cancer, autoimmune diseases, viral infections, etc. Programmed cell death occurs through complex cascades of cell signaling in which Bcl-2 family members, among others, play an important role.The Bcl-2 family of proteins regulate apoptosis as well as execute death signals at the mitochondrion. Members of this family include both pro- and anti-apoptotic proteins that hare homology sequences called Bcl-2 Homology domains (BH1-4) which mediate dimmer formation. The BH3 proteins, such as BID, NOXA, PUMA, BIK, BIM and BAD are all pro-apoptotic and share sequence homology within the amphipathic alpha-helical BH3 region, which is required for their apoptotic function. They may trigger release of death-inducing molecules such as Cytochrome C, Smac, and endonuclease G. Anti-apoptotic family members, including Bcl-2 and Bcl-XL, play inhibitory roles. Bcl-2 family proteins may form homodimers or heterodimers between pro- and anti-apoptotic members, the ratios of which determine the cell fate.

General readings

Hsu SY, Kaipia A, McGee E, et al. bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members. Proc. Natl. Acad. Sci. USA 1997; 94:12401-6.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BOK / BCL2L9 (N-term) antibody

Immunohistochemistry of BOK in human brain tissue with BOK antibody at 5 ug/mL. Rabbit IgG Aff - Purified Hu E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

BOK / BCL2L9 antibody

BOK / BCL2L9 Rabbit Aff - Purified Rt WB
0.1 mg / €410.00
  Acris Antibodies GmbH

BOK / BCL2L9 (BH3 Domain) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BOK / BCL2L9 (C-term) antibody

Human Colon, Submucosal Plexus: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Hu P
50 µg / €470.00
  Acris Antibodies GmbH

BOK / BCL2L9 (N-term) antibody

BOK Antibody (N-term) (Cat. #AP50382PU-N) western blot analysis in 293 cell line lysates (35µg/lane).This demonstrates the BOK antibody detected the BOK protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BOK / BCL2L9 (N-term) Control Peptide

BOK / BCL2L9
50 µg / €160.00
  Acris Antibodies GmbH

BOK / BCL2L9 antibody

BOK / BCL2L9 Rabbit Ms, Rt WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

BOK / BCL2L9 antibody

BOK / BCL2L9 Mouse IgG RB0969-RB0970 Purified Hu, Ms E, IP, WB
0.1 mg / €530.00
  Novus Biologicals Inc.

BOK / BCL2L9 antibody

BOK / BCL2L9 Rabbit IgG Aff - Purified Ms, Rt WB
0.1 mg / €510.00
  Novus Biologicals Inc.

BOK / BCL2L9 antibody

BOK / BCL2L9 Rabbit Aff - Purified Hu P
50 µg / €480.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

BOK / BCL2L9

BOK / BCL2L9 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

BOK / BCL2L9

BOK / BCL2L9 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

BOK / BCL2L9

BOK / BCL2L9 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

BOK / BCL2L9

BOK / BCL2L9 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

14 Item(s)

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