Alternative names for BPIL2 antibody
Bactericidal/permeability-increasing protein-like 2
Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C)
Background of BPIL2 antibody
Members of the bactericidal/permeability-increasing protein family have antimicrobial properties and bind lipophilic substances, therefore targeting gram-negative bacteria. The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). Sharing structural and sequence homologies with BPI, BPIL2 (Bactericidal/permeability-increasing protein-like 2) is a 507 amino acid secreted protein that contains the familyâ€™s common conserved feature of two cysteine residues that are critical for protein function. While BPIL2 is expressed in the basal layer of inflamed epidermis from psoriasis patients, it is not detected in normal skin.