BPNT1 antibody

Principal name

BPNT1 antibody

Alternative names for BPNT1 antibody

3'(2'),5'-bisphosphate nucleotidase 1, Bisphosphate 3'-nucleotidase 1, PAP-inositol-1,4-phosphatase

SwissProt ID

O95861 (Human), Q3ZCK3 (Bovin), Q9Z0S1 (Mouse), Q9Z1N4 (Rat)

Gene ID

10380 (BPNT1), 23827 (Bpnt1), 64473

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), African clawed frog

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of BPNT1 antibody

BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase\'s physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase\'s physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

General readings

Tessier PM, Lindquist S.
Prion recognition elements govern nucleation, strain specificity and species barriers.
Nature. 2007 May 31;447(7144):556-61. Epub 2007 May 9.
PMID: 17495929

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BPNT1 (C-term) antibody

  Goat Polyclonal Antibody against BPNT1  
TA303272 (1µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BPNT1 antibody

  Rabbit Polyclonal Anti-BPNT1 Antibody - N-terminal region  
WB Suggested Anti-BPNT1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: MCF7 cell lysate Rabbit IgG Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

BPNT1 (C-term) antibody

BPNT1 Antibody (C-term) (Cat. #AP50387PU-N) western blot analysis in Hela cell line lysates (35µg/lane).This demonstrates the BPNT1 antibody detected the BPNT1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

BPNT1 - human gene knockout kit via CRISPR

BPNT1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

BPNT1 - human gene knockout kit via CRISPR

BPNT1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

BPNT1 - human gene knockout kit via CRISPR

BPNT1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

BPNT1 - human gene knockout kit via CRISPR

BPNT1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bpnt1 - mouse gene knockout kit via CRISPR

Bpnt1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Bpnt1 - mouse gene knockout kit via CRISPR

Bpnt1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bpnt1 - mouse gene knockout kit via CRISPR

Bpnt1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bpnt1 - mouse gene knockout kit via CRISPR

Bpnt1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

BPNT1

  Recombinant protein of human 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1)  
BPNT1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

BPNT1 (1-308, His-tag)

BPNT1 Human Purified > 90 % E. coli
0.25 mg / €750.00
  Acris Antibodies GmbH

BPNT1 (1-308, His-tag)

BPNT1 Human Purified > 90 % E. coli
50 µg / €300.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BPNT1 (mGFP-tagged) - Human 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1), 200 uL, >10^7 TU/mL

Lenti ORF particles, BPNT1 (mGFP-tagged) - Human 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1), 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, BPNT1 (Myc-DDK tagged) - Human 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, BPNT1 (Myc-DDK tagged) - Human 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1) , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Bpnt1 (GFP-tagged) - Mouse bisphosphate 3'-nucleotidase 1 (Bpnt1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Bpnt1 (GFP-tagged) - Mouse bisphosphate 3'-nucleotidase 1 (Bpnt1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bpnt1 (Myc-DDK-tagged) - Mouse bisphosphate 3'-nucleotidase 1 (Bpnt1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Bpnt1 (Myc-DDK-tagged) - Mouse bisphosphate 3'-nucleotidase 1 (Bpnt1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Bpnt1 (GFP-tagged ORF) - Rat 3'(2'), 5'-bisphosphate nucleotidase 1 (Bpnt1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Bpnt1 (GFP-tagged ORF) - Rat 3'(2'), 5'-bisphosphate nucleotidase 1 (Bpnt1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bpnt1 (Myc-DDK-tagged ORF) - Rat 3'(2'), 5'-bisphosphate nucleotidase 1 (Bpnt1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Bpnt1 (Myc-DDK-tagged ORF) - Rat 3'(2'), 5'-bisphosphate nucleotidase 1 (Bpnt1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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