BRE / BRCC45 antibody

Principal name

BRE / BRCC45 antibody

Alternative names for BRE / BRCC45 antibody

BRE, BRCC45, BRCA1-A complex subunit BRE, BRCA1/BRCA2-containing complex subunit 45, Brain and reproductive organ-expressed protein

SwissProt ID

Q9NXR7 (Human)

Gene ID

9577 (BRE)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of BRE / BRCC45 antibody

BRCC45 was initially suggested to be a housekeeping protein that is highly expressed in brain and reproductive organs. Later experiments indicated BRCC45 forms a complex with the breast and ovarian predisposition proteins BRCA1 and BRCA2 as well as RAD51 and BRCC36. This complex has a ubiquitin E3 ligase activity and is thought to enhance cellular survival following DNA damage. BRCC45 has also been suggested to function as a death receptor associated anti apoptotic protein by inhibiting the BID induced activation of the mitochondrial apoptotic pathway. Higher levels of BRCC45 were detected in the majority of hepatocellular carcinomas, suggesting that BRCC45 may promote tumorigenesis when overexpressed. At least three isoforms of BRCC45 are known to exist.

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  2. Highly Validated (3)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BRE / BRCC45 antibody

BRCC45 antibody detects BRE protein by Western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug A431 whole cell lysate/extract. 10 % SDS-PAGE. BRCC45 antibody (TA307887) dilution: 1:1000 Rabbit IgG Aff - Purified Hu, Ms ICC/IF, IP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BRE / BRCC45 antibody

BRCC45 antibody detects BRE protein by Western blot analysis. A. 30 ug A431 whole cell lysate/extract. B. 30 ug HeLa whole cell lysate/extract. 10 % SDS-PAGE. BRCC45 antibody (TA307888) dilution: 1:1000 Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BRE / BRCC45 (9-338) antibody

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Bov, Hu, Ms, Rt, Ze ICC/IF, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

BRE / BRCC45 antibody

Western blot analysis of BRCC45 in HeLa cell lysate in (A) the absence and (B) presence of blocking peptide with BRCC45 antibody at 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BRE / BRCC45 antibody

Western blot analysis of extracts from Jurkat cells, using BRE antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BRE / BRCC45 antibody

Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

BRE / BRCC45 Control Peptide

BRE / BRCC45
50 µg / €160.00
  Acris Antibodies GmbH

BRE / BRCC45 antibody

Immunofluorescence of purified MaxPab antibody to BRE on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

BRE / BRCC45 antibody

Immunohistochemistry of BRE in human brain tissue with BRE polyclonal antibody ( Cat # PAB13011 ) at 2.5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

BRE / BRCC45 antibody

Immunofluorescence:   BRE Antibody [NBP1-32304]-  analysis of HeLa, using BRE antibody at 1:200 dilution. Rabbit IgG Hu ICC/IF, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

BRE / BRCC45 antibody

Immunohistochemistry: BRE Antibody [NBP1-33038] - Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using NBP1-33038. Rabbit IgG Hu ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

BRE / BRCC45 antibody

Immunohistochemistry-Paraffin: BRE Antibody [NBP1-88359] - staining of human kidney shows strong positivity in tubuli. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

BRE / BRCC45

BRE / BRCC45 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

BRE / BRCC45

BRE / BRCC45 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

BRE 293T Cell Transient Overexpression Lysate(Denatured)

BRE 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

BRE overexpression lysate

BRE overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

BRE overexpression lysate

BRE overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

BRE overexpression lysate

BRE overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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