BRIP1 / FANCJ antibody

Principal name

BRIP1 / FANCJ antibody

Alternative names for BRIP1 / FANCJ antibody

BACH1, Protein FACJ, Fanconi anemia group J protein, ATP-dependent RNA helicase BRIP1, BRCA1-interacting protein C-terminal helicase 1, BRCA1-associated C-terminal helicase 1

SwissProt ID

Q3YK19 (Chick), Q5SXJ3 (Mouse), Q9BX63 (Human)

Gene ID

83990 (BRIP1)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of BRIP1 / FANCJ antibody

This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009].

General readings

. Menichini, P., & Linial, M. SUVi and BACH1: a new subfamily of mammalian helicases? Mut. Res. 487: 67-71, 2001.
2. Ohira, M., et al. Characterization of a human homolog (BACH1) of the mouse Bach1 gene encoding a BTB-basic leucine zipper transcription factor and its mapping to chromosome 21q22.1. Genomics. 47:300-306, 1998.
3. Bridge, W. et al. The BRIP1 helicase function independently of BRCA1 in the Fanconi anemia pathway for DNA crosslink repair. Nature Genetics in press August 2005.
4. Levitis, M. et. al. The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J. Nature Genetics in press August 2005.
5. Cantor, S., et al. The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations. PNAS. 101(8): 2357-2362, 2004. (Insect)
6. Clapperton J.A., et al. Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer. Nature Struct. & Mol. Biol. 11(6):512-518, 2004.
7. Yu, X., et al. The BRCT domain is a phospho-protein binding protein. Science 302:639-642, 2003. 1. Cantor, S., et al. BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cell 105: 149-160, 2001. (Western Blot, Immunoprecipitation, human)

15 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BRIP1 / FANCJ antibody

Brip 1 detected in cell lysates using anti-BRIP1. Lane 1: MCF-7 lysate, Lane 2: HeLa lysate, Lane 3: 293 lysate and Lane 4: SKOV3 lysate. Rabbit Purified Hu C, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BRIP1 / FANCJ antibody

BRIP1 detected in 293 cell lysate using anti-BRIP1. Mouse IgG1 pp15-IB4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BRIP1 / FANCJ antibody

WB using Anti-BACH1 antibody shows detection of a band at ~105 kDa (lane 1) corresponding to human BACH1 present in a 293 whole cell lysate (arrowhead). Lane 2 shows that specific band staining is competed out when the antibody is pre-incubated with the peptide immunogen prior to reaction. The primary antibody was diluted to 1:1,000. IRDye™800 conjugated Gt-a-Rabbit IgG [H&L] MX was used at 1:10000. Rabbit Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BRIP1 / FANCJ antibody

ELISA: FANCJ Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

BRIP1 / FANCJ (1233-1249) antibody

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Mky, Prim E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

BRIP1 / FANCJ (N-term) antibody

BRIP1 Antibody (N-term) (Cat. #AP50391PU-N) western blot analysis in Jurkat cell line lysates (35µg/lane).This demonstrates the BRIP1 antibody detected the BRIP1 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BRIP1 / FANCJ antibody

BRIP1 / FANCJ Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

BRIP1 / FANCJ antibody

BRIP1 / FANCJ Mouse IgG1 GO11-3E6 Hu WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

BRIP1 / FANCJ antibody

BRIP1 detected in 293 cell lysate using BRIP1 monoclonal antibody, clone pp15-IB4 ( Cat # MAB2402 ). Mouse IgG1 pp15-IB4 Hu WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

BRIP1 / FANCJ antibody

Western blot analysis of BRIP1 in cell lysates using BRIP1 polyclonal antibody ( Cat # PAB12468 ). Lane 1 : MCF-7 lysate, Lane 2 : HeLa lysate, Lane 3 : 293 lysate and Lane 4 : SKOV3 lysate. Rabbit Hu IP, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

BRIP1 / FANCJ antibody

ELISA: FANCJ Antibody [22070002] Rabbit Hu E, WB
50 µg / €440.00
  Novus Biologicals Inc.

BRIP1 / FANCJ antibody

BRIP1 / FANCJ Mouse IgG1 pp15-IB4 Ascites Hu IP, WB
25 µl / €160.00
  Novus Biologicals Inc.

BRIP1 / FANCJ antibody

BRIP1 / FANCJ Mouse IgG1 GO11-3E6 Ascites Hu WB
0.1 ml / €360.00
  Novus Biologicals Inc.

BRIP1 / FANCJ antibody

BRIP1 / FANCJ Mouse IgG1 GO11-3E6 Hu WB
25 µl / €160.00
  Novus Biologicals Inc.

BRIP1 / FANCJ antibody

BRIP1 / FANCJ Rabbit Hu IP, P, WB
25 µl / €170.00
  Novus Biologicals Inc.

15 Item(s)

per page
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