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BRS3 antibody

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Principal name

BRS3 antibody

Alternative names for BRS3 antibody

BRS-3, Bombesin receptor subtype-3

SwissProt ID

O54798 (Mouse), P32247 (Human), Q8K418 (Rat)

Gene ID

680 (BRS3), 12209 (Brs3), 260319

Ncbi ID

9606, NP_001718.1, NP_001718, AAI52939.1, NM_001727, NP_033896.2, NM_009766, NM_152845

Available reactivities

Hu (Human), Bt (Bat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Mky (Monkey), Ms (Mouse), Prim (Primate), Rb (Rabbit), Rt (Rat), Sh (Sheep), Bear, Chk (Chicken), Hst (Hamster), Op (Opossum), Xen (Xenopus), Tr (Turkey)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of BRS3 antibody

Bombesin receptor 3 (BB3) is a member of a family of receptors that binds the 14 amino acid peptide bombesin. Bombesin was first isolated from frog skin and it was later established that mammalians express endogenous bombesin like peptides such as gastrin-releasing peptide (GRP) a 27 amino acid homologue and neuromedin B (NMB) a 10 amino acid homologue. BB1 is the preferred receptor for NMB while BB2 is the preferred receptor for GRP. BB3 was the third member of the bombesin receptors family to be cloned based in its sequence similarity to BB1 and BB2. The affinity of BB3 for bombesin is lower than that of the BB1 and BB2 receptors as is its affinity for NMB and GRP. This suggests that the mammalian endogenous ligand for the BB3 receptor remains to be identified. All three bombesin receptors are members of the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily. BB3 is coupled to a Gq/11 protein that activates phospholipase C (PLC) and leads to production of inositol 1,4,5-trisphosphate (InsP3), intracellular Ca2+ mobilization and cell growth. The physiological function of the BB3 receptor is not clear. However, studies with BB3 receptor deficient mice have shown that the mice develop mild obesity associated with hypertension and reduced metabolic rate. Filly, BB3 receptor expression has been identified in several human tumors most notably lung. BB3 is therefore considered a potential target for the development of both diagnostics and anti-cancer therapies.

AP06858PU-N - BRS3
Brain, thalamus: Formalin-Fixed Paraffin-Embedded (FFPE)
AP06859PU-N - BRS3
Brain, thalamus: Formalin-Fixed Paraffin-Embedded (FFPE)
AP06968PU-N - BRS3
Uterus, pregnant: Formalin-Fixed Paraffin-Embedded (FFPE)
AP01209PU-N - BRS3
Western blot (WB) analysis of BRS-3 antibody (Cat.-No.: AP01209PU-N) in extracts from HUVEC cells.
AP01209PU-N - BRS3

Western blot (WB) analysis of BRS-3 antibody (Cat.-No.: AP01209PU-N) in extracts from A549 and hela cells.


AP01294PU-N - BRS3
Western blot (WB) analysis of BRS-3 antibody (Cat.-No.: AP01294PU-N) at 1/500 dilution
Lane1:HEK293T cell lysate
Lane2:NIH-3T3 cell lysate
Lane3:H9C2 cell lysate
G034-1 - BRS3
Immunofluorescence analysis of A549 cells, using BRS3 Antibody. The picture on the right is treated with the synthesized peptide.
G034-1 - BRS3
Western blot analysis of extracts from HuvEc cells, using BRS3 Antibody. The lane on the right is treated with the synthesized peptide.
G217-1 - BRS3
Western blot analysis of extracts from HuvEc cells, using BRS3 Antibody. The lane on the right is treated with the synthesized peptide.
AP50393PU-N - BRS3
Western blot analysis of BRS3 Antibody (Center) (Cat. #AP50393PU-N) in mouse stomach tissue lysates (35µg/lane). BRS3 (arrow) was detected using the purified Pab
CPA1110-100ul - BRS3
Western blot analysis of BRS3 expression in MDAMB231 (A); H4 (B); PC3 (C) whole cell lysates.
TA313526 - BRS3
Western blot analysis of extracts from HUVEC cells, using BRS3 antibody.The lane on the right is treated with the synthesized peptide.
TA328616 - BRS3
Western blot analysis of rat brain membranes: 1. Anti-Bombesin Receptor 3 (extracellular) antibody, (1:200). 2. Anti-Bombesin Receptor 3 (extracellular) antibody, preincubated with the control peptide antigen.
TA328616 - BRS3
Western blot analysis of human malignant melanoma cell line Malme-3M (lanes 1 and 3) and human normal skin fibroblast cell line Malme-3 (lanes 2 and 4): 1, 2. Anti-Bombesin Receptor 3 (extracellular) antibody, (1:500). 3, 4. Anti-Bombesin Receptor 3 (extracellular) antibody, preincubated with the control peptide antigen.
TA328616 - BRS3
Western blot analysis of mouse brain lysate: 1. Anti-Bombesin Receptor 3 (extracellular) antibody, (1:200). 2. Anti-Bombesin Receptor 3 (extracellular) antibody, preincubated with the control peptide antigen.
TA328616 - BRS3
Expression of Bombesin Receptor 3 in rat testes. Immunohistochemical staining of paraffin embedded rat testes section using Anti-Bombesin Receptor 3 (extracellular) antibody, (1:50). The area of the efferent ductules near the epididymis is shown. Intense stain (brown) is specific for the pseudostratified epithelium of the efferent ductules. DAB is used for the color reaction. H&E is used as the counterstain.
TA328616 - BRS3
Indirect flow cytometry analysis in human promyelocytic leukemia HL-60 cells: black line, Unstained cells + goat-anti-rabbit-FITC. green line, Cells + Anti-Bombesin Receptor 3 (extracellular) antibody, (5 µg) + goat-anti-rabbit-FITC.
TA340505 - BRS3
Anti-BRS3 antibody IHC of human placenta, villi. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA340505 - BRS3
Anti-BRS3 antibody IHC of human pregnant uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA340506 - BRS3
Anti-BRS3 antibody IHC of human placenta, villi. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA340865 - BRS3
Anti-BRS3 antibody IHC of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA340878 - BRS3
Anti-BRS3 antibody IHC of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA340945 - BRS3
Anti-BRS3 antibody IHC of human uterus, pregnant. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA341167 - BRS3
Brain: Formalin-Fixed Paraffin-Embedded (FFPE)
TA351014 - BRS3
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: A172 cells, Primary antibody: (BRS3 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
TA351014 - BRS3
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (BRS3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
TA351014 - BRS3
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using (BRS3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BRS3 antibody
  Rabbit Polyclonal Anti-Bombesin Receptor 3 (extracellular)  
Western blot analysis of rat brain membranes: 1. Anti-Bombesin Receptor 3 (extracellular) antibody, (1:200). 2. Anti-Bombesin Receptor 3 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €622.00
  OriGene Technologies, Inc.
+4 additional images

Highly validated antibody!

BRS3 antibody
  Rabbit polyclonal anti-BRS3 antibody  
Western blot analysis of extracts from HUVEC cells, using BRS3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

BRS3 (N-term) antibody
  Rabbit Polyclonal Anti-BRS3 Antibody (N-Terminus)  
BRS3 Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €400.00
  OriGene Technologies, Inc.

BRS3 (C-term) antibody
  Rabbit Polyclonal Anti-BRS3 Antibody (C-Terminus)  
BRS3 Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

BRS3 (2nd Extracell. Dom.) antibody
  Rabbit Polyclonal Anti-BRS3 Antibody (Extracellular Domain)  
BRS3 Rabbit Aff - Purified Hu, Mky, Prim P
50 µg / €400.00
  OriGene Technologies, Inc.

BRS3 (C-term, cytopl. dom.) antibody
  Rabbit Polyclonal Anti-BRS3 Antibody (C-Terminus)  
BRS3 Rabbit Aff - Purified Bt, Elephant, Hu, Mky, Prim P
50 µg / €400.00
  OriGene Technologies, Inc.

BRS3 antibody
  Rabbit Polyclonal Anti-BRS3 Antibody (Extracellular Domain)  
Anti-BRS3 antibody IHC of human uterus, pregnant. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu
50 µg / €400.00
  OriGene Technologies, Inc.

BRS3 (3rd cytopl. dom.) antibody
  Rabbit Polyclonal Anti-BRS3 Antibody (Cytoplasmic Domain)  
BRS3 Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, GP, Hst, Hu, Mky, Ms, Prim, Rb, Rt, Sh P
50 µg / €400.00
  OriGene Technologies, Inc.

BRS3 antibody
  Rabbit Polyclonal Anti-BRS3 Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: A172 cells, Primary antibody: (BRS3 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+2 additional images

BRS3 antibody
Western blot (WB) analysis of BRS-3 antibody (Cat.-No.: AP01209PU-N) in extracts from HUVEC cells. Rabbit Aff - Purified Hu ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH
+1 additional image

BRS3 antibody
Western blot (WB) analysis of BRS-3 antibody (Cat.-No.: AP01294PU-N) at 1/500 dilution Lane1:HEK293T cell lysate Lane2:NIH-3T3 cell lysate Lane3:H9C2 cell lysate Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

BRS3 (N-term extracell. dom.) antibody
Brain, thalamus: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Mky E, P
50 µg / €380.00
  Acris Antibodies GmbH

BRS3 (C-term cytopl. dom.) antibody
Brain, thalamus: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu E, P
50 µg / €380.00
  Acris Antibodies GmbH

BRS3 (1st Cytopl. Dom.) antibody
Uterus, pregnant: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Bov, Bt, Can, Elephant, Eq, GP, Hst, Hu, Mky, Ms, Platypus, Rb, Rt, Sh E, P
50 µg / €380.00
  Acris Antibodies GmbH

BRS3 (Center) antibody
Western blot analysis of BRS3 Antibody (Center) (Cat. #AP50393PU-N) in mouse stomach tissue lysates (35µg/lane). BRS3 (arrow) was detected using the purified Pab Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BRS3 antibody
Immunofluorescence analysis of A549 cells, using BRS3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech
+1 additional image

BRS3 antibody
Immunofluorescence analysis of A549 cells, using BRS3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech
+1 additional image

BRS3 antibody
Western blot analysis of extracts from HuvEc cells, using BRS3 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Assay Biotech

BRS3 antibody
Western blot analysis of extracts from HuvEc cells, using BRS3 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

BRS3 - human gene knockout kit via CRISPR
BRS3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

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33 products - FILTER YOUR RESULTS!

Available Filters

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Clonality
  1. Polyclonal (19)
Target
  1. BRS3 (19)
Property
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Reactivity
  1. Human (Hu) (19)
  2. Mouse (Ms) (6)
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  5. Bat (Bt) (3)
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  12. Hamster (Hst) (2)
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Applications
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  3. Paraffin Sections (P) (9)
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  1. 1 image (14)
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  1. GFP-Puro (2)
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Manufacturer
  1. Acris - OriGene (29)
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Service
  • OriGene EU
  • Acris Antibodies GmbH
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  • D-32052 Herford
  • Germany
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