BRS3 antibody
Principal name
BRS3 antibody
Alternative names for BRS3 antibody
BRS-3, Bombesin receptor subtype-3
Ncbi ID
9606, NP_001718.1, NP_001718, AAI52939.1, NM_001727, NP_033896.2, NM_009766, NM_152845
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of BRS3 antibody
Bombesin receptor 3 (BB3) is a member of a family of receptors that binds the 14 amino acid peptide bombesin. Bombesin was first isolated from frog skin and it was later established that mammalians express endogenous bombesin like peptides such as gastrin-releasing peptide (GRP) a 27 amino acid homologue and neuromedin B (NMB) a 10 amino acid homologue. BB1 is the preferred receptor for NMB while BB2 is the preferred receptor for GRP. BB3 was the third member of the bombesin receptors family to be cloned based in its sequence similarity to BB1 and BB2. The affinity of BB3 for bombesin is lower than that of the BB1 and BB2 receptors as is its affinity for NMB and GRP. This suggests that the mammalian endogenous ligand for the BB3 receptor remains to be identified. All three bombesin receptors are members of the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily. BB3 is coupled to a Gq/11 protein that activates phospholipase C (PLC) and leads to production of inositol 1,4,5-trisphosphate (InsP3), intracellular Ca2+ mobilization and cell growth. The physiological function of the BB3 receptor is not clear. However, studies with BB3 receptor deficient mice have shown that the mice develop mild obesity associated with hypertension and reduced metabolic rate. Filly, BB3 receptor expression has been identified in several human tumors most notably lung. BB3 is therefore considered a potential target for the development of both diagnostics and anti-cancer therapies.

Western blot (WB) analysis of BRS-3 antibody (Cat.-No.: AP01209PU-N) in extracts from A549 and hela cells.

Lane1:HEK293T cell lysate
Lane2:NIH-3T3 cell lysate
Lane3:H9C2 cell lysate















- Quick-Filters:
- Highly Validated (1)
Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA328616 | BRS3 antibody |
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Rabbit Polyclonal Anti-Bombesin Receptor 3 (extracellular) | |||||||
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Rabbit | Purified | Hu, Ms, Rt | WB |
0.2 ml /
€622.00
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OriGene Technologies, Inc. | |||||||
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Highly validated antibody! |
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TA313526 | BRS3 antibody |
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Rabbit polyclonal anti-BRS3 antibody | |||||||
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Rabbit | IgG | Purified | Hu | E, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
TA340505 | BRS3 (N-term) antibody |
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Rabbit Polyclonal Anti-BRS3 Antibody (N-Terminus) | |||||||
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Rabbit | Aff - Purified | Hu, Ms, Rt | P |
50 µg /
€400.00
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OriGene Technologies, Inc. | |||||||
TA340506 | BRS3 (C-term) antibody |
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Rabbit Polyclonal Anti-BRS3 Antibody (C-Terminus) | |||||||
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Rabbit | Aff - Purified | Hu | P |
50 µg /
€400.00
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OriGene Technologies, Inc. | |||||||
TA340865 | BRS3 (2nd Extracell. Dom.) antibody |
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Rabbit Polyclonal Anti-BRS3 Antibody (Extracellular Domain) | |||||||
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Rabbit | Aff - Purified | Hu, Mky, Prim | P |
50 µg /
€400.00
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OriGene Technologies, Inc. | |||||||
TA340878 | BRS3 (C-term, cytopl. dom.) antibody |
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Rabbit Polyclonal Anti-BRS3 Antibody (C-Terminus) | |||||||
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Rabbit | Aff - Purified | Bt, Elephant, Hu, Mky, Prim | P |
50 µg /
€400.00
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OriGene Technologies, Inc. | |||||||
TA340945 | BRS3 antibody |
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Rabbit Polyclonal Anti-BRS3 Antibody (Extracellular Domain) | |||||||
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Rabbit | Purified | Hu |
50 µg /
€400.00
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OriGene Technologies, Inc. | |||||||
TA341167 | BRS3 (3rd cytopl. dom.) antibody |
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Rabbit Polyclonal Anti-BRS3 Antibody (Cytoplasmic Domain) | |||||||
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Rabbit | Aff - Purified | Bear, Bov, Bt, Can, Elephant, Eq, GP, Hst, Hu, Mky, Ms, Prim, Rb, Rt, Sh | P |
50 µg /
€400.00
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OriGene Technologies, Inc. | |||||||
TA351014 | BRS3 antibody |
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Rabbit Polyclonal Anti-BRS3 Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
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AP01209PU-N | BRS3 antibody |
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Rabbit | Aff - Purified | Hu | ICC/IF, WB |
0.1 mg /
€350.00
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Acris Antibodies GmbH | |||||||
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AP01294PU-N | BRS3 antibody |
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Rabbit | Aff - Purified | Hu | E, ICC/IF, WB |
0.1 mg /
€350.00
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Acris Antibodies GmbH | |||||||
AP06858PU-N | BRS3 (N-term extracell. dom.) antibody |
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Rabbit | Aff - Purified | Hu, Mky | E, P |
50 µg /
€380.00
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Acris Antibodies GmbH | |||||||
AP06859PU-N | BRS3 (C-term cytopl. dom.) antibody |
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Rabbit | Aff - Purified | Hu | E, P |
50 µg /
€380.00
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Acris Antibodies GmbH | |||||||
AP06968PU-N | BRS3 (1st Cytopl. Dom.) antibody |
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Rabbit | Aff - Purified | Bov, Bt, Can, Elephant, Eq, GP, Hst, Hu, Mky, Ms, Platypus, Rb, Rt, Sh | E, P |
50 µg /
€380.00
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Acris Antibodies GmbH | |||||||
AP50393PU-N | BRS3 (Center) antibody |
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Rabbit | Ig | Aff - Purified | Hu, Ms | WB |
0.4 ml /
€370.00
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Acris Antibodies GmbH | |||||||
G034-1 | BRS3 antibody |
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Rabbit | Aff - Purified | Hu | E, ICC/IF, WB |
50 µg /
€230.00
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Assay Biotech | |||||||
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G034-2 | BRS3 antibody |
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Rabbit | Aff - Purified | Hu | E, ICC/IF, WB |
0.1 mg /
€330.00
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Assay Biotech | |||||||
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G217-1 | BRS3 antibody |
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Rabbit | Aff - Purified | Hu | E, WB |
50 µg /
€230.00
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Assay Biotech | |||||||
G217-2 | BRS3 antibody |
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Rabbit | Aff - Purified | Hu | E, WB |
0.1 mg /
€330.00
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Assay Biotech |
CRISPR
Catalog No. | Species | Donor Vector | |
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KN213923 | BRS3 - human gene knockout kit via CRISPR |
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Human | GFP-Puro |
1 kit /
€1,290.00
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OriGene Technologies, Inc. |