BRSK1 antibody

Principal name

BRSK1 antibody

Alternative names for BRSK1 antibody

KIAA1811, SAD1, SAD-B, BR serine/threonine-protein kinase 1, SAD1 kinase, Serine/threonine kinase SAD-B

SwissProt ID

Q5RJI5 (Mouse), Q8TDC3 (Human)

Gene ID

84446 (BRSK1), 381979 (Brsk1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of BRSK1 antibody

BRSK1 was initially identified as a mammalian homolog to the fission yeast S. pombe Cdr2, a mitosis-regulatory kinase and also shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK1 is unbiquitously expressed, with highest levels of expression in the brain and testes. Similar to its yeast homolog, BRSK1 is thought to be involved in stress-induced cell cycle arrest. Overexpression of this protein leads to the G2/M arrest in HeLa S2 cells and UV-induced G2/M arrest could be partially abrogated by reduced expression of BRSK1 through the use of siRNA, indicating its role in DNA damage checkpoint function. More recently, it has been shown that both BRSK1 and the related protein BRSK2 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. At least two isoforms of BRSK1 are known to exist.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BRSK1 (C-term) antibody

Brain, cortex: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

BRSK1 (C-term) antibody

  Rabbit Polyclonal BRSK1 Antibody  
Western blot analysis of BRSK1 in human brain tissue lysate with BRSK1 antibody at (A) 0.5 and (B) 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BRSK1 (Center) antibody

  Rabbit Polyclonal BRSK1 Antibody  
Western blot analysis of BRSK1 in human brain tissue lysate with BRSK1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BRSK1 antibody

  Rabbit polyclonal anti-BRSK1 antibody  
Western blot analysis of extracts from 293 cells, using BRSK1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BRSK1 antibody

Brain, cortex: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

BRSK1 (N-term) antibody

Western blot analysis of anti-KIAA181 Pab in mouse liver tissue lysate (35ug/lane). KIAA181(arrow) was detected using the purified Pab (1:60 dilution). Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BRSK1 antibody

Western blot analysis of extracts from 293 cells, using BRSK1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €230.00
  Assay Biotech

BRSK1 antibody

Western blot analysis of extracts from 293 cells, using BRSK1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

BRSK1 - human gene knockout kit via CRISPR

BRSK1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

BRSK1 - human gene knockout kit via CRISPR

BRSK1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

BRSK1 - human gene knockout kit via CRISPR

BRSK1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

BRSK1 - human gene knockout kit via CRISPR

BRSK1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Brsk1 - mouse gene knockout kit via CRISPR

Brsk1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Brsk1 - mouse gene knockout kit via CRISPR

Brsk1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Brsk1 - mouse gene knockout kit via CRISPR

Brsk1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Brsk1 - mouse gene knockout kit via CRISPR

Brsk1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

BRSK1 overexpression lysate

BRSK1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BRSK1 (mGFP-tagged)-Human BR serine/threonine kinase 1 (BRSK1), 200 uL, >10^7 TU/mL

Lenti ORF particles, BRSK1 (mGFP-tagged)-Human BR serine/threonine kinase 1 (BRSK1), 200 uL, >10^7 TU/mL  
200 µl / €1,690.00
  OriGene Technologies, Inc.

Lenti ORF particles, BRSK1 (Myc-DDK-tagged)-Human BR serine/threonine kinase 1 (BRSK1), 200 uL, >10^7 TU/mL

Lenti ORF particles, BRSK1 (Myc-DDK-tagged)-Human BR serine/threonine kinase 1 (BRSK1), 200 uL, >10^7 TU/mL  
200 µl / €1,520.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Brsk1 (GFP-tagged) - Mouse BR serine/threonine kinase 1 (Brsk1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Brsk1 (GFP-tagged) - Mouse BR serine/threonine kinase 1 (Brsk1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,480.00
  OriGene Technologies, Inc.

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